Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

SML2438

Sigma-Aldrich

Magnolin

≥95% (HPLC)

Synonym(s):

Magnolin, (+)-Magnolin, (1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)tetrahydro-4-(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan, Medioresinol dimethyl ether, (1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)tetrahydro-4-(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan

Sign Into View Organizational & Contract Pricing

Select a Size

5 MG
₪319.00
25 MG
₪770.00

₪319.00

Please contact Customer Service for Availability
Request a Bulk Order
All Photos(1)

Select a Size

Change View
5 MG
₪319.00
25 MG
₪770.00

About This Item

Empirical Formula (Hill Notation):
C23H28O7
CAS Number:
31008-18-1
Molecular Weight:
416.46
MDL number:
MFCD07783722
UNSPSC Code:
12352200
NACRES:
NA.77

₪319.00

Please contact Customer Service for Availability
Request a Bulk Order

Assay

≥95% (HPLC)

form

powder

optical activity

[α]/D +46 to +56°, c = 0.5 in chloroform-d

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

[H][C@]12[C@]([C@@H](C3=CC(OC)=C(OC)C(OC)=C3)OC2)([H])CO[C@@H]1C4=CC=C(OC)C(OC)=C4

InChI

1S/C23H28O7/c1-24-17-7-6-13(8-18(17)25-2)21-15-11-30-22(16(15)12-29-21)14-9-19(26-3)23(28-5)20(10-14)27-4/h6-10,15-16,21-22H,11-12H2,1-5H3/t15-,16-,21+,22+/m0/s1

InChI key

MFIHSKBTNZNJIK-RZTYQLBFSA-N

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Magnolin is a main component of Magnolia flos the exhibits anti-inflammatory, antioxidative, and vasodilatory activities. Magnolin inhibits cell migration and invasion by targeting the ERKs/RSK2 signaling. Also magnolin protects against renal tubular necrosis, apoptosis, and the deterioration of renal function in contrast-induced nephropathy (CIN) in rats.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000063197
0000063198
0000054640

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Feng Wang et al.
Oxidative medicine and cellular longevity, 2014, 203458-203458 (2014-11-18)
Magnolin is the major active ingredient of the herb Magnolia fargesii which has anti-inflammatory and antioxidative effects. Oxidative stress and apoptosis are involved in the pathogenesis of contrast-induced nephropathy (CIN). We hypothesize that Magnolin could protect against CIN through antioxidative
Yeqing Huang et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 87, 714-720 (2017-01-17)
Magnolin is the most active ingredient in the herb Magnolia fargesii, which has been traditionally used in oriental medicine to treat headaches and nasal congestion. Recent researches demonstrate that Magnolin inhibits cancer cell migration and invasion. This study used cell
Cheol-Jung Lee et al.
BMC cancer, 15, 576-576 (2015-08-09)
Magnolin is a natural compound abundantly found in Magnolia flos, which has been traditionally used in oriental medicine to treat headaches, nasal congestion and anti-inflammatory reactions. Our recent results have demonstrated that magnolin targets the active pockets of ERK1 and

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service