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SML0463

Sigma-Aldrich

BPD

≥98% (HPLC)

Synonym(s):

3-(1,3-benzodioxol-5-yl)-4-phenyl-2,5-Furandione

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About This Item

Empirical Formula (Hill Notation):
C17H10O5
CAS Number:
213481-12-0
Molecular Weight:
294.26
MDL number:
MFCD22666591
UNSPSC Code:
12352200
PubChem Substance ID:
329824741

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 15 mg/mL (clear solution)

storage temp.

−20°C

SMILES string

O=C1OC(=O)C(c2ccc3OCOc3c2)=C1c4ccccc4

InChI

1S/C17H10O5/c18-16-14(10-4-2-1-3-5-10)15(17(19)22-16)11-6-7-12-13(8-11)21-9-20-12/h1-8H,9H2

InChI key

IMHGOAWBSJVILI-UHFFFAOYSA-N

Biochem/physiol Actions

BPD inhibits LPS-induced NF-kB signaling by inactivation of TAK-1. BPD is also known to inhibit the expression and activity of COX-2.
BPD inhibits LPS-induced NF-kB signaling; COX-2 inhibitor.

Features and Benefits

This compound is featured on the Cytokine Receptors (Interleukin-1 Receptor/TIR Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H302,H400

Precautionary Statements

P273

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
082M4618V

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