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SAB4503316

Sigma-Aldrich

Anti-CASP7 (p20, Cleaved-Asp198) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Apoptotic protease Mch-3, CASP-7, Caspase-7, ICE-LAP3, ICE-like apoptotic protease 3

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100 μG
₪1,751.00

₪1,751.00

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100 μG
₪1,751.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

₪1,751.00

Please contact Customer Service for Availability

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 20 kDa

species reactivity

human, mouse

concentration

~1 mg/mL

technique(s)

ELISA: 1:40000
western blot: 1:500-1:1000

NCBI accession no.

P55210

UniProt accession no.

P55210

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

proteolytically cleaved (Asp198)

Gene Information

human ... CASP7(840)

General description

Anti-CSPN7 (p20, Cleaved-Asp198) Antibody detects endogenous levels of fragment of activated CSPN7 (p20, Cleaved-Asp198) protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human Caspase 7.

Immunogen Range: 149-198

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
410165

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Shuo-Shuo Liu et al.
Nature communications, 15(1), 891-891 (2024-01-31)
Procaspase 9 is the initiator caspase for apoptosis, but how its levels and activities are maintained remains unclear. The gigantic Inhibitor-of-Apoptosis Protein BIRC6/BRUCE/Apollon inhibits both apoptosis and autophagy by promoting ubiquitylation of proapoptotic factors and the key autophagic protein LC3

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