SAB4503258
Anti-Calnexin, C-Terminal antibody produced in rabbit
affinity isolated antibody
Synonym(s):
CALX, CANX, IP90, Major histocompatibility complex class I
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100 μG
₪2,334.00
₪2,334.00
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100 μG
₪2,334.00
About This Item
₪2,334.00
Please contact Customer Service for Availability
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biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 67 kDa
species reactivity
mouse, rat, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CANX(821)
General description
Anti-Calnexin Antibody detects endogenous levels of total Calnexin protein.
CANX (calnexin) is an endoplasmic reticulum (ER) chaperone. It has a molecular weight of 67kDa. It is a type I transmembrane protein and is located on human chromosome 5q35.
Immunogen
The antiserum was produced against synthesized peptide derived from human Calnexin.
Immunogen Range: 543-592
Immunogen Range: 543-592
Biochem/physiol Actions
CANX (calnexin) participates in protein folding and quality control. It is responsible for glycan-independent interaction and retention of mutated Gas3/PMP22 (growth arrest-specific protein 3/peripheral myelin protein 22) proteins involved in Charcot-Marie-Tooth 1A and Dejerine Sottas syndrome.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Hao Liu et al.
Cell biology international, 43(2), 167-173 (2018-12-15)
Cerebral dopamine neurotrophic factor (CDNF) has been considered as potent candidates for the therapy of Parkinson's disease (PD) for which can promote the survival of midbrain dopaminergic neurons. In addition to secret out from cells like other classical neurotrophic factors
Mapping of primary congenital lymphedema to the 5q35.3 region
Evans AL, et al.
American Journal of Human Genetics, 64(2), 547-555 (1999)
Silvia G Inderbinen et al.
Toxicology letters, 322, 39-49 (2020-01-14)
Exposure to the environmental pollutants organotins is of toxicological concern for the marine ecosystem and sensitive human populations, including pregnant women and their unborn children. Using a placenta cell model, we investigated whether organotins at nanomolar concentrations affect the expression
Hao Liu et al.
Cell biology international, 43(2), 167-173 (2018-12-15)
Cerebral dopamine neurotrophic factor (CDNF) has been considered as potent candidates for the therapy of Parkinson's disease (PD) for which can promote the survival of midbrain dopaminergic neurons. In addition to secret out from cells like other classical neurotrophic factors
Michael Weingartner et al.
PLoS neglected tropical diseases, 16(1), e0009192-e0009192 (2022-01-15)
Echinococcus multilocularis causes alveolar echinococcosis (AE), a rising zoonotic disease in the northern hemisphere. Treatment of this fatal disease is limited to chemotherapy using benzimidazoles and surgical intervention, with frequent disease recurrence in cases without radical surgery. Elucidating the molecular
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