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SAB2500391

Sigma-Aldrich

Anti-FEM1C antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-EUROIMAGE686608, Anti-EUROIMAGE783647, Anti-FEM1A, Anti-KIAA1785

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, mouse

technique(s)

indirect ELISA: suitable
western blot: suitable

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... FEM1C(56929)

General description

Fem-1 homolog C (FEM1C) is a homolog of the Fem-1 gene of Caenorhabditis elegans. It is predicted to encode an ankyrin repeat proteins which is expressed in many tissues. FEM1C is a conserved VHL-box protein. The gene encoding it is localized on human chromosome 5q22.

Immunogen

Peptide with sequence C-HIPEKLETFVSLHR from the C Terminus of the protein sequence according to NP_064562.1.

Biochem/physiol Actions

Fem-1 homolog C (FEM1C) is a substrate recognition subunit of cullin-2-RING E3 ubiquitin ligase complex. It has a role in the degradation of stem-loop binding protein (SLBP).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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FEM1 proteins are ancient regulators of SLBP degradation.
Dankert JF
Cell Cycle (2017)
FEM1A and FEM1B: novel candidate genes for polycystic ovary syndrome.
Goodarzi MO
Human Reproduction (2008)
The Fem1c genes: conserved members of the Fem1 gene family in vertebrates.
Ventura-Holman
Gene (2003)

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