synthetic peptide corresponding to the N-terminal extracellular domain of human somatostatin receptor type 4, conjugated to KLH. The immunizing peptide has 50% homology with the rat gene and 38% homology with the mouse gene.
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The Journal of clinical endocrinology and metabolism, 99(5), E891-E901 (2014-02-12)
Somatostatin (SST) receptors (SSTRs) are expressed in a number of tissues, including the adrenal cortex, but their role in cortisol secretion has not been well characterized. The objective of the study was to investigate the expression of SSTRs in the
Journal of cellular and molecular medicine, 13(9B), 3283-3295 (2009-05-12)
The recently suggested pivotal role of somatostatin (SOM) receptor 4 (SSTR4) in inflammation and nociception in several non-intestinal organs and in gastrointestinal (GI) physiology, necessitates exploration of the role of SSTR4 in GI pathophysiology. Therefore, the role of SSTR4 in
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 19(7), 596-606 (2007-06-27)
Despite our knowledge of somatostatin (SOM) in gastrointestinal functions, little information is available on the SOM receptors (SSTRs) mediating these effects. This study focussed on the expression of SSTRs in non-inflamed and Schistosoma mansoni-infected murine ileum using immunocytochemistry, reverse transcriptase
American journal of physiology. Gastrointestinal and liver physiology, 297(2), G406-G417 (2009-05-30)
The course of intestinal inflammatory responses is tightly coordinated by the extensive communication between the immune system and the enteric nervous system, among which the bidirectional mast cell-neuron interaction within the intestinal wall plays a prominent role. Recent research suggests
British journal of cancer, 110(9), 2232-2245 (2014-04-20)
Malignant pleural mesothelioma (MPM) is an aggressive neoplasm arising from mesothelial lining of pleura. CD26 molecules preferentially expressed on epithelioid type of MPM. This study investigates the molecular mechanisms of CD26 regulating MPM cells in vitro and in vivo. Biochemical
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