P102
R(+)-3-(3-Hydroxyphenyl)-N-propylpiperidine hydrochloride
solid
Synonym(s):
R(+)-3-PPP hydrochloride
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 mg | Please contact Customer Service for Availability | ₪639.00 | |
| 100 mg | Please contact Customer Service for Availability | ₪1,289.00 |
About This Item
Empirical Formula (Hill Notation):
C14H21NO · HCl
CAS Number:
Molecular Weight:
255.78
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Form:
solid
Quality level:
form
solid
Quality Level
color
white
solubility
H2O: 150 mg/mL, ethanol: slightly soluble
SMILES string
Cl.CCCN1CCC[C@@H](C1)c2cccc(O)c2
InChI
1S/C14H21NO.ClH/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12;/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3;1H/t13-;/m0./s1
InChI key
NRHUDETYKUBQJT-ZOWNYOTGSA-N
Gene Information
human ... DRD2(1813)
Biochem/physiol Actions
D2 dopamine receptor agonist. Also functions as σ1 receptor antagonist with essentially no affinity for the phencylidine site on the NMDA receptor.
Preparation Note
Solutions should be freshly prepared.
Legal Information
Sold with the permission of Astra Pharmaceutical Co.
1 of 1
This Item | |||
|---|---|---|---|
| form solid | form solid | form solid | form solid |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| solubility H2O: 150 mg/mL, ethanol: slightly soluble | solubility H2O: 50 mg/mL, slightly hazy, faintly yellow | solubility H2O: >5 mg/mL | solubility H2O: soluble |
| color white | color - | color white | color white |
| Gene Information human ... DRD2(1813) | Gene Information - | Gene Information human ... DRD1(1812) | Gene Information - |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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M C Coldwell et al.
British journal of pharmacology, 127(5), 1135-1144 (1999-08-24)
This study characterized pharmacologically the functional responses to agonists at human dopamine D2(long) (hD2), D3 (hD3) and D4.4 (hD4) receptors separately expressed in cloned cells using the cytosensor microphysiometer. Dopaminergic receptor agonists caused increases in extracellular acidification rate in adherent
R Bergeron et al.
Psychopharmacology, 129(3), 215-224 (1997-02-01)
Several high affinity sigma (sigma) ligands, such as DTG, JO-1784, (+)-pentazocine, BD-737 and L-687,384, administered at low doses act as agonists by potentiating N-methyl-D-aspartate (NMDA)-induced activation of pyramidal neurons in the CA3 region of the rat dorsal hippocampus. This potentiation
S Tokuyama et al.
Neuroscience letters, 233(2-3), 141-144 (1997-11-14)
We studied effects of various sigma ligands on GTPase activity in mouse prefrontal membranes. Some representative sigma agonists, such as (+)-pentazocine, SA4503 and (+)-3-PPP, stimulated the GTPase activity in a concentration-dependent manner in ranges of 10 nM to 10 microM.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P102-25MG | 04061832092508 |
| P102-100MG | 04061832083551 |