G8166
Glucagon-Like Peptide 2 -Arg human trifluoroacetate salt
>90% (HPLC), solid
Synonym(s):
GLP-2-Arg, Preproglucagon 126-159
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| Size/SKU | Availability | Price |
|---|---|---|
0.5 mg | Please contact Customer Service for Availability | ₪2,841.00 |
About This Item
Empirical Formula (Hill Notation):
C171H266N48O56S
CAS Number:
Molecular Weight:
3922.29
UNSPSC Code:
51111800
NACRES:
NA.32
MDL number:
General description
Application
Glucagon-Like Peptide 2 (GLP-2) -Arg human trifluoroacetate salt has been used for injection in chickens to determine the effects of GLP-2 on the weight and morphology of small intestines.[1]
Biochem/physiol Actions
Glucagon-like peptide 2 (GLP-2) influences the functionality of gastrointestinal tract by participating in the feedback loop to the brain for the control of food intake. It also controls digestion and absorption, and has tropic effects post chemotherapy injury or surgical resection.[1] This peptide is also responsible for epithelial cell proliferation of the small bowel.[3] Studies in rats show that this peptide enhances the effects of the ileal-brake hormones, GLP-1 and peptide YY. It also negatively regulates gastrointestinal motility and secretion. Thus, it has potential as a therapeutic agent in short-bowel syndrome.[2]
Glucagon-like peptide 2 is a neuropeptide that inhibits food intake when injected into the lateral ventricles of the brain and may mediate satiety. It is also a growth factor that stimulates proliferation and blocks apoptosis of intestinal epithelial cells.
Neuropeptide that inhibits food intake when injected into the lateral ventricles of the brain and may mediate satiety; also a growth factor that stimulates proliferation and blocks apoptosis of intestinal epithelial cells.
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This Item | |||
|---|---|---|---|
| assay >90% (HPLC) | assay ≥97% (HPLC) | assay ≥96% (HPLC) | assay ≥97% (HPLC) |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| form solid | form powder | form - | form solid |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| Gene Information human ... GCG(2641) | Gene Information human ... GCG(2641) | Gene Information human ... GCG(2641) | Gene Information human ... PYY(5697) |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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