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biological source
algae (Macrocystis pyrifera)
Assay
≥85%
form
powder
color
white to brown
working range
4-7
solubility
water: 10 mg/mL, clear to hazy, colorless to very faintly brown
storage temp.
room temp
Related Categories
General description
Fucoidan is a fucose-rich, sulfated polysaccharide isolated from several species of brown seaweed.
Biochem/physiol Actions
Studies of fucoidan have found it to have a broad variety of biological activities including antitumor and antiangogenic activities, immunomodulatory, anti-inflammatory, anticoagulant, antithrombotic, and antioxidant activities. Fucoidan induces macrophage activation which subsequently activates mitogen activated protein kinases (MAPKs) and results in natural killer cell proliferation. Fucoidan acts as a nonselective selectin blocker and has been shown to induce apoptosis and suppress angiogenesis.
Other Notes
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Anna Pielesz et al.
The Analyst, 140(13), 4599-4607 (2015-06-02)
Differential scanning calorimetry (DSC) and thermogravimetric (TGA) investigations, acetate electrophoresis (CAE), Fourier-transform infrared spectrometry (FTIR), scanning electron microscopy (SEM) analysis and microbiological procedures were all carried out after heating the samples to a temperature sufficient for simulating a burn incident.
Xiang Li et al.
Arteriosclerosis, thrombosis, and vascular biology, 34(8), 1661-1667 (2014-06-07)
Nuclear imaging of active plaques still remains challenging. Advanced atherosclerotic plaques have a strong expression of P-selectin by the endothelium overlying active atherosclerotic plaques, but not on the endothelium overlying inactive fibrous plaques. We proposed a new approach for noninvasive
Wentong Cui et al.
Laboratory investigation; a journal of technical methods and pathology, 94(4), 382-393 (2014-03-13)
Endothelial dysfunction, characterized by impairment of endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) bioavailability, has been implicated in diabetic cardiovascular pathogenesis. In this study, low-molecular-weight fucoidan (LMWF), which has multiple biological activities including anti-inflammatory and anti-oxidative properties, was
G Heim et al.
The British journal of nutrition, 111(9), 1577-1585 (2014-02-08)
In the present study, two experiments were conducted to (1) evaluate the effect of laminarin and/or fucoidan on ileal morphology, nutrient transporter gene expression and coefficient of total tract apparent digestibility (CTTAD) of nutrients and (2) determine whether laminarin inclusion
Yuangang Liu et al.
Journal of nanoscience and nanotechnology, 14(5), 3844-3849 (2014-04-17)
Fucoidan was chosen a substitute for alginate in chitosan-based polyelectrolytes or polyiones because it is negatively charged and possesses pharmacological properties. The fucoidan-chitosan nanospheres were prepared by the sonification method, and different formulation variables were investigated to get regular and
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