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F0752

D-Fructose 1,6-bisphosphate tetra(cyclohexylammonium) salt

≥95% anhydrous basis (enzymatic)

Synonym(s):

D(+)Fructofuranose 1,6-diphosphate, Harden-Young ester, Hexose diphosphate

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5 g
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₪915.00
10 g
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₪1,657.00

About This Item

Empirical Formula (Hill Notation):
C6H14O12P2 · 4C6H13N
CAS Number:
103213-44-1
Molecular Weight:
736.81
MDL number:
MFCD00135876
UNSPSC Code:
12352201
PubChem Substance ID:
329799667
NACRES:
NA.25

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biological source

synthetic (organic)

Quality Level

200

assay

≥95% anhydrous basis (enzymatic)

form

powder

impurities

Hexose monophosphates, essentially free

color

white to off-white

solubility

water: 100 mg/mL, clear to hazy, colorless to faintly yellow

storage temp.

−20°C

SMILES string

NC1CCCCC1.NC2CCCCC2.NC3CCCCC3.NC4CCCCC4.O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)C(=O)COP(O)(O)=O

InChI

1S/4C6H13N.C6H14O12P2/c4*7-6-4-2-1-3-5-6;7-3(1-17-19(11,12)13)5(9)6(10)4(8)2-18-20(14,15)16/h4*6H,1-5,7H2;3,5-7,9-10H,1-2H2,(H2,11,12,13)(H2,14,15,16)/t;;;;3-,5-,6-/m....1/s1

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This Item
G5875G6526F6803
D-Fructose 1,6-bisphosphate tetra(cyclohexylammonium) salt ≥95% anhydrous basis (enzymatic)

Sigma-Aldrich

F0752

D-Fructose 1,6-bisphosphate tetra(cyclohexylammonium) salt

α-D-Glucose 1,6-bisphosphate tetra(cyclohexylammonium) salt hydrate ≥95% dry basis

Sigma-Aldrich

G5875

α-D-Glucose 1,6-bisphosphate tetra(cyclohexylammonium) salt hydrate

D-Glucose 6-phosphate potassium salt ≥95% anhydrous basis (enzymatic)

Sigma-Aldrich

G6526

D-Glucose 6-phosphate potassium salt

D-Fructose 1,6-bisphosphate trisodium salt hydrate ≥98% (TLC)

Sigma-Aldrich

F6803

D-Fructose 1,6-bisphosphate trisodium salt hydrate

assay

≥95% anhydrous basis (enzymatic)

assay

≥95% dry basis

assay

≥95% anhydrous basis (enzymatic)

assay

≥98% (TLC)

biological source

synthetic (organic)

biological source

synthetic

biological source

synthetic (organic)

biological source

microbial

solubility

water: 100 mg/mL, clear to hazy, colorless to faintly yellow

solubility

water: 50 mg/mL, clear, colorless to very faintly yellow

solubility

water: 50 mg/mL, clear to hazy, colorless

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

200

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Application

D-Fructose-1,6-bisphosphate (FBP) may be used as an allosteric activator of enzymes such as pyruvate kinase and NAD+-dependent L-(+)-lactate dehydrogenase, as an inhibitor of acetate kinase and as a substrate to identify and characterize enzymes such as fructose-1,6-bisphosphate aldolase(s) and fructose-1, 6-bisphosphatase(s). FBP is studied as a neuroprotective agent in brain injury.

Biochem/physiol Actions

D-Fructose-1,6-bisphosphate (FBP), a common metabolic sugar, is the precursor of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic pathway.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000539687
0000523200
0000539687
0000523200
0000521060

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Scott D Pegan et al.
Journal of molecular biology, 386(4), 1038-1053 (2009-01-27)
Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), currently infects one-third of the world's population in its latent form. The emergence of multidrug-resistant and extensive drug-resistant strains has highlighted the need for new pharmacological targets within M. tuberculosis. The class
Paul D van Poelje et al.
Handbook of experimental pharmacology, 203(203), 279-301 (2011-04-13)
Fructose-1,6-bisphosphatase (FBPase), a rate-controlling enzyme of gluconeogenesis, has emerged as an important target for the treatment of type 2 diabetes due to the well-recognized role of excessive endogenous glucose production (EGP) in the hyperglycemia characteristic of the disease. Inhibitors of
Javier Modrego et al.
Journal of vascular surgery, 55(4), 1124-1133 (2012-01-10)
The purpose of this study was to evaluate the expression of proteins related to cytoskeleton and energetic metabolism at abdominal aortic aneurysm (AAA) sites using proteomics. Several remodeling-related mechanisms have been associated with AAA formation but less is known about
Chao Wang et al.
Molecular biology reports, 39(4), 5017-5024 (2011-12-14)
This study investigated whether there were single nucleotide polymorphisms (SNPs) in fructose-1,6-bisphosphate aldolase (FBA) gene associated with growth traits of the clam Meretrix meretrix. A FBA gene was identified in M. meretrix and its deduced amino acid residues shared high
Jonathan H Martin et al.
Journal of bacteriology, 200(17) (2018-06-20)
DeoR-type helix-turn-helix (HTH) domain proteins are transcriptional regulators of sugar and nucleoside metabolism in diverse bacteria and also occur in select archaea. In the model archaeon Haloferax volcanii, previous work implicated GlpR, a DeoR-type transcriptional regulator, in the transcriptional repression
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Global Trade Item Number

SKUGTIN
F0752-10G04061832389431
F0752-5G04061833611364

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