D8941

2,6-Difluoro-4-[2-(phenylsul­fonyl­amino)­ethyl­thio]­phenoxy­acet­amide

≥98% (HPLC), solid

• Synonym(s): PEPA
• Empirical Formula (Hill Notation): C₁₆H₁₆N₂O₄S₂F₂
• CAS Number: 141286-78-4
• Molecular Weight: 402.44
• NACRES: NA.77
• PubChem Substance ID: 24278571
• UNSPSC Code: 12352200
• MDL number: MFCD04974493
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: protect from light

Properties

• assay: ≥98% (HPLC)
• form: solid
• storage condition: protect from light
• color: white
• solubility: DMSO: >20 mg/mL
• SMILES string: NC(=O)COc1c(F)cc(SCCNS(=O)(=O)c2ccccc2)cc1F
• InChI: 1S/C16H16F2N2O4S2/c17-13-8-11(9-14(18)16(13)24-10-15(19)21)25-7-6-20-26(22,23)12-4-2-1-3-5-12/h1-5,8-9,20H,6-7,10H2,(H2,19,21)
• InChI key: GTACSIONMHMRPD-UHFFFAOYSA-N
• Gene Information: human ... GRIA1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893)

Description

Biochem/physiol Actions

2,6-Difluoro-4-[2-(phenylsul­fonyl­amino)­ethyl­thio]­phenoxy­acet­amide is a structurally novel, selective, high affinity AMPA ionotropic glutamate receptor agonist that reduces ischemia-induced performance deficits in rats.

2,6-Difluoro-4-[2-(phenylsul­fonyl­amino)­ethyl­thio]­phenoxy­acet­amide is a structurally novel, selective, high affinity AMPA ionotropic glutamate receptor agonist.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)