C2051
[Asn-OH17]-Conantokin G
≥97% (HPLC)
Synonym(s):
Conantokin-G
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About This Item
Empirical Formula (Hill Notation):
C88H138N26O44
CAS Number:
Molecular Weight:
2264.19
MDL number:
UNSPSC Code:
12352200
Assay
≥97% (HPLC)
storage temp.
−20°C
Amino Acid Sequence
Gly-Glu-γ-CarboxyGlu-γ-CarboxyGlu-Leu-Gln-γ-CarboxyGlu-Asn-Gln-γ-CarboxyGlu-Leu-Ile-Arg-γ-CarboxyGlu-Lys-Ser-Asn
Linkage
Carboxy-terminal free acid analog of sleep-inducing peptide conantokin-G
Certificates of Analysis (COA)
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J A Haack et al.
The Journal of biological chemistry, 265(11), 6025-6029 (1990-04-15)
Conantokin-T, a 21-amino acid peptide which induces sleep-like symptoms in young mice was purified from the venom of the fish-hunting cone snail, Conus tulipa. The amino acid sequence of the peptide was determined and verified by chemical synthesis. The peptide
B M Olivera et al.
Science (New York, N.Y.), 249(4966), 257-263 (1990-07-20)
Conus venoms contain a remarkable diversity of pharmacologically active small peptides. Their targets are ion channels and receptors in the neuromuscular system. The venom of Conus geographus contains high-affinity peptides that act on voltage-sensitive calcium channels, sodium channels, N-methyl-D-aspartate (NMDA)
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