B8061

N-Butyl-N-(4-hydroxybutyl)nitrosamine

ISOPAC^®, ≥90% (GC)

• Synonym(s): BBN, N-Butyl-N-butan-4-ol-nitrosamine, N-Butyl-N-nitroso-4-aminobutanol, OH-BBN
• Empirical Formula (Hill Notation): C₈H₁₈N₂O₂
• CAS Number: 3817-11-6
• Molecular Weight: 174.24
• MDL number: MFCD00059008
• UNSPSC Code: 12352116
• NACRES: NA.25
• Assay: ≥90% (GC)
• Form: liquid

Properties

• Quality Segment: 200
• assay: ≥90% (GC)
• form: liquid
• storage temp.: 2-8°C
• SMILES string: N(N=O)(CCCCO)CCCC
• InChI: 1S/C8H18N2O2/c1-2-3-6-10(9-12)7-4-5-8-11/h11H,2-8H2,1H3
• InChI key: DIKPQFXYECAYPC-UHFFFAOYSA-N

Description

Application

N-Butyl-N-(4-hydroxybutyl)nitrosamine (BBN), a carcinogen, is used to induce histiologically relevant aggressive urinary bladder cancer in animal models.

Biochem/physiol Actions

Carcinogen used to induce urinary bladder cancer in animal models. The result of exposure is histologically comparable to human urinary bladder tumorigenesis. Used in chemopreventative studies.

Packaging

Packaged in a 100 mL serum bottle with butyl rubber stopper and aluminum tear seal.

Preparation Note

Dissolving the contents in 100 mL of solvent yields a 1% solution.

Legal Information

Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Injecting any compatible solvent permits preparation of any desired strength solution without exposure.

Safety Information

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H350
• pcodes: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 1B
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: 296.6 °F
• flash_point_c: 147 °C
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter