A5566

Monoclonal Anti-α₁-Acid Glycoprotein antibody produced in mouse

clone AGP-47, ascites fluid

• UNSPSC Code: 12352203
• NACRES: NA.41
• MDL number: MFCD00162118
• Conjugate: unconjugated
• Clone: AGP-47, monoclonal
• Application: DB, ELISA (i), WB
• Citations: 5

Properties

• biological source: mouse
• Quality Segment: 200
• conjugate: unconjugated
• antibody form: ascites fluid
• antibody product type: primary antibodies
• clone: AGP-47, monoclonal
• contains: 15 mM sodium azide
• species reactivity: human, baboon (weakly)
• should not react with: canine, bovine
• technique(s): dot blot: suitable, indirect ELISA: suitable, western blot: 1:10,000
• isotype: IgG1
• UniProt accession no.: P02763
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ORM1(5004)

Description

General description

Monoclonal Anti-α1-Acid Glycoprotein (mouse IgG1 isotype) is derived from the AGP-47 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice. α1-Acid Glycoprotein (AGP) is an acute-phase plasma protein. This protein is mainly produced in the hepatocytes. AGP1 gene is mapped on the human chromosome at 9q32.

Immunogen

human α₁-acid glycoprotein (AGP).

Biochem/physiol Actions

α1-Acid Glycoprotein (AGP) associates with haptoglobin and C-reactive protein, which indicates inflammation. Higher levels of AGP is associated with various inflammatory diseases, trauma, malignancies, myocardial infarction, rheumatoid arthritis, after major surgery, and in cases of chronic pain. This protein is capable of binding and transporting basic and neutral drugs.

Recognizes an epitope located on the 44 kDa subunit of denatured-reduced AGP using the immunoblotting technique. It does not cross react with human serum amyloid P component, human haptoglobin, human C-reactive protein, and human IgG.

Physical form

The product is provided as ascites fluid with 0.1% sodium azide as a preservative.

Preparation Note

For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable