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92860

Sigma-Aldrich

Glyceryl trioleate

≥97.0% (TLC)

Synonym(s):

TG(18:1(9Z)/18:1(9Z)/18:1(9Z)), (9Z)9-Octadecenoic acid 1,2,3-propanetriyl ester, 1,2,3-Tri(cis-9-octadecenoyl)glycerol, Glycerol trioleate, Glycerol triolein, Oleic acid triglyceride, Oleic triglyceride, TG(18:1(9Z)/18:1(9Z)/18:1(9Z)), Triolein

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About This Item

Linear Formula:
(C17H33COOCH2)2CHOCOC17H33
CAS Number:
122-32-7
Molecular Weight:
885.43
Beilstein:
1718692
EC Number:
204-534-7
MDL number:
MFCD00137563
UNSPSC Code:
41141833
PubChem Substance ID:
57653498
NACRES:
NA.25

biological source

plant
synthetic

Assay

≥97.0% (TLC)

form

liquid

composition

18:1, ~98% (fatty acid)

bp

235-240 °C/18 mmHg (lit.)

solubility

chloroform: 0.1 g/mL, clear, colorless

density

0.91 g/mL (lit.)

functional group

ester

lipid type

neutral glycerides

storage temp.

2-8°C

SMILES string

[H]C(COC(CCCCCCC/C=C\CCCCCCCC)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

InChI

1S/C57H104O6/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-55(58)61-52-54(63-57(60)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)53-62-56(59)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h25-30,54H,4-24,31-53H2,1-3H3/b28-25-,29-26-,30-27-

InChI key

PHYFQTYBJUILEZ-IUPFWZBJSA-N

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Application


  • Development of lipid-based SEDDS using digestion products of long-chain triglyceride for high drug solubility: Formulation and dispersion testing.: This study discusses the formulation of self-emulsifying drug delivery systems (SEDDS) using products from the digestion of glyceryl trioleate, aiming to enhance drug solubility and bioavailability (Desai et al., 2024).

  • Encapsulation and retention of chelated-copper inside hydrophobic nanoparticles: Liquid cored nanoparticles show better retention than a solid core formulation.: Research on encapsulating copper complexes in nanoparticles with glyceryl trioleate components to improve delivery and retention, comparing solid and liquid cores (Hervella et al., 2016).

Storage Class Code

10 - Combustible liquids

WGK

awg

Flash Point(F)

626.0 °F - closed cup

Flash Point(C)

330.0 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Mira Rosenblat et al.
BioFactors (Oxford, England), 38(4), 292-299 (2012-06-08)
We analyzed, for the first time, both in vitro and in vivo, the effect of very low density lipoprotein (VLDL), or of pure triglycerides, on high-density lipoprotein (HDL)-associated paraoxonase1 (PON1) catalytic activities. Incubation of serum or HDL from healthy subjects
Mi-Hwa Lee et al.
Applied and environmental microbiology, 78(14), 4959-4966 (2012-05-01)
A novel lipolytic enzyme was isolated from a metagenomic library obtained from tidal flat sediments on the Korean west coast. Its putative functional domain, designated MPlaG, showed the highest similarity to phospholipase A from Grimontia hollisae CIP 101886, though it
Yuqiang Tao et al.
Environmental science & technology, 46(7), 3851-3858 (2012-03-01)
Although numerous studies have addressed sequestration of hydrophobic organic compounds (HOCs) in laboratory, little attention has been paid to its evaluation method in field at large temporal scale. A biomimetic tool, triolein embedded cellulose acetate membrane (TECAM), was therefore tested
Sylvie Hollebeeck et al.
Food chemistry, 138(2-3), 1936-1944 (2013-02-16)
Bioaccessibility studies should be taken into account when evaluating the physiological effects of ingested compounds at the intestine level. Several in vitro digestion protocols have been described, with a wide range of experimental conditions but no optimised protocol exists. In
Jonathan C Jun et al.
American journal of physiology. Endocrinology and metabolism, 303(3), E377-E388 (2012-05-25)
Obstructive sleep apnea (OSA) induces intermittent hypoxia (IH) during sleep and is associated with elevated triglycerides (TG). We previously demonstrated that mice exposed to chronic IH develop elevated TG. We now hypothesize that a single exposure to acute hypoxia also
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