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18360

Sigma-Aldrich

Bromosulfalein

for microscopy (Hist.)

Synonym(s):

Phenoltetrabromophthalein-3′,3″-disulfonic acid disodium salt, Sulfobromophthalein disodium salt

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About This Item

Empirical Formula (Hill Notation):
C20H8Br4Na2O10S2
CAS Number:
71-67-0
Molecular Weight:
838.00
EC Number:
200-761-0
MDL number:
MFCD00012442
UNSPSC Code:
12171500
PubChem Substance ID:
57647735
Pricing and availability is not currently available.

grade

for microscopy (Hist.)

suitability

suitable for microscopy

SMILES string

[Na+].[Na+].OC(=O)c1c(Br)c(Br)c(Br)c(Br)c1\C(c2ccc(O)c(c2)S([O-])(=O)=O)=C3/C=CC(=O)C(=C3)S([O-])(=O)=O

InChI

1S/C20H10Br4O10S2.2Na/c21-16-14(15(20(27)28)17(22)19(24)18(16)23)13(7-1-3-9(25)11(5-7)35(29,30)31)8-2-4-10(26)12(6-8)36(32,33)34;;/h1-6,25H,(H,27,28)(H,29,30,31)(H,32,33,34);;/q;2*+1/p-2/b13-8+;;

InChI key

HXUITPQMHVLBNV-LIYVDSPJSA-L

Application

Reagent for the quantitative determination of proteins.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H317,H334

Precautionary Statements

P261 - P280 - P342 + P311

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBH3552V
BCBB7176V
BCBC1863V
BCBC1863
BCBB7176

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Mirko Leonhardt et al.
Drug metabolism and disposition: the biological fate of chemicals, 38(7), 1024-1028 (2010-04-22)
Contrast-enhancing magnetic resonance imaging with the liver-specific agent gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) has been shown to improve the detection rate of focal lesions. There is evidence from preclinical studies that multidrug organic anion transporters are involved in hepatic uptake of
Anja Joachim et al.
Experimental parasitology, 127(4), 762-767 (2011-01-19)
Sulphobromophthalein (SBP) inhibits isolated glutathione S-transferase of the porcine nodule worm Oesophagostomum dentatum (Od-GST) and reduces larval development in vitro. In this study possible inhibitory effects of various inhibitors were evaluated in an enzymatic (CDNB) assay with isolated Od-GST and
Juergen Kindla et al.
Drug metabolism and disposition: the biological fate of chemicals, 39(6), 1047-1053 (2011-03-11)
The transporter-mediated uptake of drugs from blood into hepatocytes is a prerequisite for intrahepatic drug action or intracellular drug metabolism before excretion. Therefore, uptake transporters, e.g., members of the organic anion transporting polypeptide (OATP) family are important determinants of drug
Wen Zhang et al.
European journal of drug metabolism and pharmacokinetics, 42(4), 669-676 (2016-11-07)
Ophiopogonin D (OPD) is one of the main active ingredients of SMI (Shenmai injection) which is widely used in clinical practice in China. Our previous study indicated  that OPD might be transported from blood into liver mediated by organic anion
Jörg König et al.
Drug metabolism and disposition: the biological fate of chemicals, 39(6), 1097-1102 (2011-03-25)
The therapeutic effects and metabolism of mesalazine (5-aminosalicylic acid) in patients with inflammatory bowel disease require intracellular accumulation of the drug in intestinal epithelial cells and hepatocytes. The molecular mechanisms of mesalazine uptake into cells have not been characterized so
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