363642

Sodium periodate

10 wt. %, matrix silica gel support

• Synonym(s): Sodium (meta)periodate
• Linear Formula: NaIO₄
• CAS Number: 7790-28-5
• Molecular Weight: 213.89
• MDL number: MFCD00003534
• UNSPSC Code: 12352300
• PubChem Substance ID: 329755344

Properties

• form: powder
• reaction suitability: reagent type: oxidant
• concentration: 10 wt. %; 9.0-11.0% (by Na₂S₂O₃, titration)
• matrix: silica gel support
• pH: 3.5-5.5 (25 °C, 107 g/L)
• mp: 300 °C (dec.) (lit.)
• SMILES string: [Na+].[O-]I(=O)(=O)=O
• InChI: 1S/HIO4.Na/c2-1(3,4)5;/h(H,2,3,4,5);/q;+1/p-1
• InChI key: JQWHASGSAFIOCM-UHFFFAOYSA-M

Description

General description

Sodium periodate (sodium (meta)periodate) supported on silica gel is a solid supported reagent. It may be synthesized by adding silica gel to hot aqueous solution of sodium metaperiodate and evaporating to dryness followed by vigorous swirling and shaking.

Application

Sodium periodate (sodium (meta)periodate) supported on silica gel may be used in the following reactions:

• Oxidative cleavage of glycols to alkenes and 1,2-diols to aldehydes.
• Phthalimide N-oxyl (PINO) radical generation from N-hydroxyphthalimide (NHPI).
• Selective oxidation of sulfides by microwave thermolysis process.
• Regeneration of ketones from ketoximes by microwave irradiation under solvent-free conditions.
• Preparation of 2,3-O-isopropylidene-D-glyceraldehyde.

Safety Information

• Pictograms: GHS03,GHS08,GHS05,GHS09
• Signal Word: Danger
• Hazard Statements: H272,H314,H372,H411
• Precautionary Statements: P210 - P260 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Aquatic Chronic 2 - Eye Dam. 1 - Ox. Sol. 2 - Skin Corr. 1C - STOT RE 1
• Target Organs: thymus gland
• Storage Class Code: 5.1A - Strongly oxidizing hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable