46968

Tolbutamide

VETRANAL^®, analytical standard

• Synonym(s): 1-Butyl-3-(4-methylphenylsulfonyl)urea, N-[(Butylamino)carbonyl]-4-methylbenzenesulfonamide
• Empirical Formula (Hill Notation): C₁₂H₁₈N₂O₃S
• CAS Number: 64-77-7
• Molecular Weight: 270.35
• Beilstein: 1984428
• EC Number: 200-594-3
• MDL number: MFCD00027169
• UNSPSC Code: 41116107
• PubChem Substance ID: 329757278
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 200
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): clinical testing
• format: neat
• SMILES string: CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1
• InChI: 1S/C12H18N2O3S/c1-3-4-9-13-12(15)14-18(16,17)11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3,(H2,13,14,15)
• InChI key: JLRGJRBPOGGCBT-UHFFFAOYSA-N
• Gene Information: human ... ABCC8(6833) , KCNJ1(3758) , KCNJ11(3767)

Description

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Anti-diabetic agent. Metabolized by CYP2C9 (tolbutamide hydroxylase).

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves