218763

Caspase-6 Substrate III, Fluorogenic

A fluorogenic substrate for caspase-6 (Mch2).

• Synonym(s): Caspase-6 Substrate III, Fluorogenic, Z-VEID-AFC
• Empirical Formula (Hill Notation): C₃₈H₄₄F₃N₅O₁₂
• CAS Number: 219138-06-4
• Molecular Weight: 819.78
• MDL number: MFCD01318833
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥95% (HPLC)
• form: lyophilized
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated; protect from light
• solubility: DMSO: 5 mg/mL
• fluorescence: λ_ex ~400 nm; λ_em ~505 nm
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: FC(F)(F)C1=CC(=O)Oc2c1ccc(c2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)OCc3ccccc3)C(C)C)CCC(=O)O)[C@H](CC)C)CC(=O)O
• InChI key: OEVAAZFKVRJQQH-UXAYAQJLSA-N

Description

General description

A fluorogenic substrate for caspase-6 (Mch2). Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore (excitation maximum: ~400 nm; emission maximum: ~505 nm).

A fluorogenic substrate for caspase-6 (Mch2). Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.

Biochem/physiol Actions

Cell permeable: no

Primary Target
A fluorogenic substrate for caspase-6 (Mch2

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Z-Val-Glu-Ile-Asp-AFC

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Hazard Statements: H413
• Precautionary Statements: P273 - P501
• Hazard Classifications: Aquatic Chronic 4
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable