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1.50154

Supelco

LiChrospher® 100 RP-18 (5 µm) HPLC Columns

L x I.D. 250 mm x 3 mm, LiChroCART™ HPLC cartridge, manuCART™ holder required for use

Synonym(s):

TM=["LiChrospher"] C18 TM=["LICHROCART"] cartridge for HPLC

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About This Item

UNSPSC Code:
41115709
NACRES:
SB.52

product name

LiChrospher® 100 RP-18 (5 µm) LiChroCART™ 250-3, suitable for HPLC

material

stainless steel column

Quality Level

100

Agency

suitable for USP L1

product line

LiChrospher®

feature

endcapped: no

packaging

1 ea of

extent of labeling

21% Carbon loading

parameter

250 bar pressure
60 °C max. temp.

technique(s)

HPLC: suitable
mass spectrometry (MS): suitable (Low - Medium)

column L × I.D.

25 cm × 3 mm

surface area

350 m2/g

matrix

fully porous particle

matrix active group

C18 bonding phase

particle size

5 μm

pore size

100 Å pore size

operating pH range

2-7.5

separation technique

reversed phase

storage temp.

no temp limit

General description

HPLC cartridge
LiChrospher® RP-18 is a reliable and versatile traditionally produced spherical silica gel carrier with C-18 reversed phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds. This sorbent is packed into a LiChroCART 250-3 HPLC cartridge. The connection to the HPLC system is being accomplished by use of the manu-CART NT cartrige holder (1.51486).

Application


  • Metronidazole and 2-Hydroxymetronidazole Rapid Detection in Murine Blood Plasma: The column facilitated rapid and accurate quantification in pharmacological studies, crucial for evaluating therapeutic responses and drug safety (Zemanova et al., 2022).

  • High-Throughput HPLC Method for Ropinirole Hydrochloride: Demonstrating its utility in developing robust HPLC methods, this column was central to optimizing procedures for neurological medications, enhancing clinical and pharmacokinetic studies (Fatima et al., 2019).

  • Comprehensive Impurity Profiling in Pharmaceutical Analysis: This column′s high resolution was instrumental in identifying and quantifying impurities in drug substances, ensuring compliance with stringent quality standards (Tengattini et al., 2019).

  • Environmental Contaminant Analysis: The column′s application extended to environmental science, where it was used to measure pollutants in complex samples, illustrating its adaptability and efficiency in environmental monitoring (Mochamad and Hermanto, 2017).

Analysis Note

Pressure: ≤ 95 bar
Theoretical Plates (N/m) (Toluene): ≥ 50000
Symmetry (Toluene): 0.8 - 1.4
Capacity factor (Toluene): 1.5 - 3.5

Legal Information

LICHROCART is a trademark of Merck KGaA, Darmstadt, Germany
LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany

Certificates of Analysis (COA)

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