1.16881
Fractogel® EMD TMAE (M)
Synonym(s):
Biochromatography, Fractogel® Ion exchangers, Ion exchanger for LC (Fractogel® TSK/EMD), Fractogel® EMD TMAE (M)
About This Item
Recommended Products
ligand
(Trimethylammoniumethyl)
Quality Level
description
strong anion exchanger, suspension in 20% ethanol and 150 mM NaCl (40-90 µm)
sterility
sterile (Caustic Stable)
product line
Fractogel®
form
resin
parameter
240 cm/hr flow rate
8 bar max. pressure
matrix active group
methacrylate
mean particle size
40-90 μm
capacity
100 mg binding capacity (BSA/mg of resin)
transition temp
flash point 35 °C (calculated)
density
1.430 g/cm3 at 20 °C
bulk density
1000 kg/m3
application(s)
gene therapy
mAb
recombinant protein
separation technique
anion exchange
strong anion exchange
storage temp.
no temp limit
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General description
Features and Benefits
- High protein loading conditions resulting in good selectivity and resolution with the tentacle technology
- Excellent binding to large viruses at increased loading
- Homogenous binding with high selectivity and purity
- Reduce operating costs and resin replacement with enduring durability - allowing for multiple cycles of column regeneration and sanitization
- Compatibility with 2.5 % (v/v) aqueous benzyl alcohol containing 150 mM NaCl storage solution
Packaging
- 1.16881.0100: Fractogel® EMD TMAE (M) Resin 100ml
- 1.16881.0010: Fractogel® EMD TMAE (M) Resin 10ml
- 1.16881.0500: Fractogel® EMD TMAE (M) Resin 500ml
- 1.16881.0050: Fractogel® EMD TMAE (M) Resin 50ml
Analysis Note
Microscopic evaluation: Uniform spherical particles,no agglomerates,no fines
Extractable matter (water): ≤ 0.03 %
Cerium: ≤ 1 µg/g
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Particle size (d10): 37 - 45 µm
Particle size (d50): 48 - 60 µm
Particle size (d90): 63 - 77 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Protein binding capacity (bovine serum albumin): 80 - 120 mg/ml
Functional test (b:a): ≤ 0.25
Functional test: Separation of conalbumin and human serum albumin
Legal Information
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Flam. Liq. 3
Storage Class Code
3 - Flammable liquids
WGK
WGK 1
Flash Point(F)
95.0 °F
Flash Point(C)
35 °C
Certificates of Analysis (COA)
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