1.08720

Thioglycollate Broth

Non animal origin irradiated granulated medium for Microbiological analysis

• Synonym(s): Fluid Thioglycollate Medium
• UNSPSC Code: 41106200
• NACRES: NA.74

Properties

• Quality Level: 400
• sterility: irradiated
• form: medium granules
• feature: granulated
• packaging: pkg of 5 kg
• manufacturer/tradename: GranuCult^®
• pH: 6.9-7.3 (25 °C, 29 g/L in H₂O)
• solubility: 29 g/L
• application(s): aseptic process simulation; pharmaceutical
• compatibility: stand alone
• storage temp.: 15-25°C
• suitability: anaerobic bacteria (facultative and microaerophilic)

Description

General description

The Granulated media is cold filterable and gamma-irradiated for the microbiological aseptic process simulation (Media Fill Test). The media are supplied in triple-wrapped and cleanroom ready for the ultimate security of aseptic process. It is granulated which guarantees excellent solubility even in cold water. Cold filterability is achieved by extensive testing comprising raw materials, pre-production samples, in-process and end product control

Application

The broth is suitable for media fill tests according to the recommendations of the “FDA Aseptic Guide” in aseptic production lines. The exclusive use of raw materials of non-animal origin allows the elimination of a potential contamination risk with TSE/BSE.

Other Notes

Mode of action: Thioglycolate Broth glucose, peptone from casein and yeast extract provide growth factors necessary for bacterial growth. The reducing agents thioglycolate and L-cystine ensure an anaerobiosis which is adequate even for fastidious anaerobes and prevent the accumulation of peroxides which are lethal to some microorganisms. The sulfhydryl groups of these substances inactivate arsenic, mercury and other heavy metal compounds. Thioglycolate media are thus suitable for the examination of materials which contain heavy metals or heavy metal preservatives.

Footnote

We offer two media types: the superior granulated GranuCult^® and the cost-efficient powdered NutriSelect^® culture media, depending on your needs.
The designations basic, plus, or prime are added to indicate the quality control level, from basic quality control to standard QC plus to prime for full regulatory compliance.

Legal Information

GRANUCULT is a registered trademark of Merck KGaA, Darmstadt, Germany

NutriSelect is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H317
• Precautionary Statements: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3