Key Documents

View All Documentation

Anti-SUMO-1 Antibody

Name: Anti-SUMO-1 Antibody
Brand: MM
Price: 2305 ILS

Upstate^®, from rabbit

Select a Size

Change View

Pack Size	SKU	Availability	Price
100 μL		Please contact Customer Service for Availability	₪2,305.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

polyclonal

Application:

Citations:

₪2,305.00

Please contact Customer Service for Availability

Request a Bulk Order

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity (predicted by homology)

all

manufacturer/tradename

Upstate^®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

NM_001005781.1, NM_001005782.1, NM_003352.4

UniProt accession no.

P63165

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SENP2(59343), SUMO1(7341)

Description

General description

The small ubiquitin-related modifier SUMO-1 belongs to the growing family of ubiquitin-related proteins involved in post translational protein modification1. It is present in all eukaryotic kingdoms and is highly conserved from yeast to humans. SUMO-1 does not appear to target proteins for degradation but seems to be involved in the modulation of protein-protein interactions. An increasing number of SUMO-1 substrates are being described but three major substrates for SUMO-1 modification are RanGAP1 and PML proteins.

Immunogen

Synthetic peptide corresponding to amino acid residues 11-101 of human SUMO-1.

Application

Anti-SUMO-1 Antibody detects level of SUMO-1 & has been published & validated for use in WB.

Biochem/physiol Actions

Recognizes SUMO-1. This antibody shows no cross-reactivity with ubiquitin, multi-ubiquitin chains, SUMO2/3, UCRP, Nedd8, and FAT10.

Physical form

100 µL of purified by salt precipitation in PBS containing 0.01% sodium azide. Dilute to working strength with 50mM Tris-HCl buffer (pH 7.6) containing 1.5% sodium chloride and 1% normal goat serum (if a goat anti-rabbit IgG linker antibody is to be used).

Format: Purified

Other Notes

Replaces: 04-453

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	07-2167	SAB1300007	MABS2039
Sigma-Aldrich 09-409 Anti-SUMO-1 Antibody	Sigma-Aldrich 07-2167 Anti-SUMO 2/3 Antibody	$Anti-Drosophila Sumo (C-term) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution$ Sigma-Aldrich SAB1300007 Anti-Drosophila Sumo (C-term) antibody produced in rabbit	Sigma-Aldrich MABS2039 Anti-SUMO-2/3 Antibody, clone 8A2
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form purified antibody	antibody form -	antibody form IgG fraction of antiserum	antibody form purified immunoglobulin
clone polyclonal	clone polyclonal	clone polyclonal	clone 8A2, monoclonal
biological source rabbit	biological source rabbit	biological source rabbit	biological source mouse
technique(s) western blot: suitable	technique(s) immunoprecipitation (IP): suitable, western blot: suitable	technique(s) indirect ELISA: 1:1000, western blot: 1:100-1:500	technique(s) immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
Gene Information human ... SENP2(59343), SUMO1(7341)	Gene Information human ... SUMO2(6613) mouse ... Sumo2(170930) opossum ... Sumo2(123244757) rat ... Sumo2(690244)	Gene Information human ... SUMO1(7341)	Gene Information human ... SUMO2(6613)

Still not finding the right product?

Try our Product Selector Tool to narrow your options

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

12 - Non Combustible Liquids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

The insulin/IGF signaling cascade modulates SUMOylation to regulate aging and proteostasis in Caenorhabditis elegans.

Lorna Moll et al.

eLife, 7 (2018-11-08)

Although aging-regulating pathways were discovered a few decades ago, it is not entirely clear how their activities are orchestrated, to govern lifespan and proteostasis at the organismal level. Here, we utilized the nematode Caenorhabditis elegans to examine whether the alteration

SUMO/sentrin: protein modifiers regulating important cellular functions.

C Kretz-Remy et al.

Biochemistry and cell biology = Biochimie et biologie cellulaire, 77(4), 299-309 (1999-11-05)

Regulation of protein functions can be achieved by posttranslational protein modifications. One of the most studied modifications has been conjugation to ubiquitin, which mainly targets substrate proteins for degradation by the 26 S proteasome. Recently, SUMO/sentrin, a ubiquitin-like protein has

Structure determination of the small ubiquitin-related modifier SUMO-1.

P Bayer et al.

Journal of molecular biology, 280(2), 275-286 (1998-07-09)

The recently discovered small ubiquitin-related modifier SUMO-1 belongs to the growing family of ubiquitin-related proteins involved in postranslational protein modification. Unlike ubiquitin, SUMO-1 does not appear to target proteins for degradation but seems to be involved in the modulation of

View All Related Papers

Global Trade Item Number

SKU	GTIN
09-409	04053252337758

Questions

Reviews

No rating value