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07-710

Anti-SMC2/hCAP-E Antibody

serum, Upstate®

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Pack SizeSKUAvailabilityPrice
100 μL
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₪2,259.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
16

₪2,259.00


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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SMC2(10592)

General description

137kDa
SMC2 and SMC4 from the active ATPase subunit of Condensin I and Condensin II complexes that regulate chromosome compaction.

Immunogen

KLH-conjugated, synthetic peptide corresponding to amino acids 1184-1197 (C-KSKAKPPKGAHVEV) of human SMC2/hCAP-E (Structural Maintenance of Chromosome 2/ Chromosome-Associated Protein E) with an N-terminal cysteine added for conjugation purposes.

Application

Anti-SMC2/hCAP-E Antibody is a high quality Rabbit Polyclonal Antibody for the detection of SMC2/hCAP-E & has been validated in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

Biochem/physiol Actions

SMC2/hCAP-E

Physical form

Serum

Preparation Note

2 years at -20°C

Analysis Note

Control
Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.
Routinely evaluated by immunoblot.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item
SAB1300671SAB1300627S7822
biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human, rat (predicted), mouse (predicted)

antibody form

serum

antibody form

saturated ammonium sulfate (SAS) precipitated

antibody form

IgG fraction of antiserum

antibody form

IgG fraction of antiserum

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

Gene Information

human ... SMC2(10592)

Gene Information

human ... SMC2(10592)

Gene Information

human ... NCAPH2(29781)

Gene Information

human ... SMC6(79677)
mouse ... Smc6(67241)
rat ... Smc6l1(313961)


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Storage Class

10 - Combustible liquids

wgk

WGK 1



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling.
Yeoh, Eng-Juh, et al.
Cancer Cell, 1, 133-143 (2002)
Alexander Schleiffer et al.
Molecular cell, 11(3), 571-575 (2003-04-02)
We describe a superfamily of eukaryotic and prokaryotic proteins (kleisins) that includes ScpA, Scc1, Rec8, and Barren. Scc1 interacts with SMC proteins through N- and C-terminal domains to form a ring-like structure. Since these are the only domains conserved among
Mingxuan Sun et al.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 26(4), 277-295 (2018-08-26)
During cell division, chromosomes must be folded into their compact mitotic form to ensure their segregation. This process is thought to be largely controlled by the action of condensin SMC protein complexes on chromatin fibers. However, how condensins organize metaphase



Global Trade Item Number

SKUGTIN
07-71004053252511974

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