06-891

Anti-SMRTe Antibody

Upstate^®, from rabbit

• Synonym(s): Anti-CTG26, Anti-N-CoR2, Anti-SMAP270, Anti-SMRT, Anti-SMRTE, Anti-SMRTE-tau, Anti-TNRC14, Anti-TRAC, Anti-TRAC-1, Anti-TRAC1
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: ChIP, ICC, WB
• Citations: 27

Properties

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human
• manufacturer/tradename: Upstate^®
• technique(s): ChIP: suitable, immunocytochemistry: suitable, western blot: suitable
• isotype: IgG
• NCBI accession no.: NM_006312
• UniProt accession no.: Q9Y618
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... NCOR2(9612), TRAC(28755)

Description

General description

270kDa, 180kDa and 80kDa

SMRT is 1495 amino acids and contains an 8 amino acid sequence that is not present in SMRTe (SMRT-extended), which contains 2514 amino acids. SMRTe contains an N-terminal sequence spanning over 1,000 amino acids that is not present in SMRT, but that shows significant similarity with N-CoR. SMRTe expression is regulated during cell cycle progression, suggesting a role for SMRTe in the regulation of cycle-specific gene expression in diverse signaling pathways.

Immunogen

GST fusion-protein corresponding to residues 1146-1349 of human SMRTe

Application

Anti-SMRTe Antibody is a high quality Rabbit Polyclonal Antibody for the detection of SMRTe & has been validated in ChIP, ICC & WB.

Research Category
Protein Trafficking

Epigenetics & Nuclear Function

Research Sub Category
RNA Metabolism & Binding Proteins

Histones

RNA Binding Protein (RBP)

Biochem/physiol Actions

SMRT isoforms

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%

Format: Purified

Protein A chromatography

Preparation Note

Store at 2–8°C

Analysis Note

Control
Mouse brain nuclear extract

routinely evaluated by immunoblot on nuclear fraction from murine brain

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable