H-099

7-Hydroxymitragynine solution

100 μg/mL in methanol with 0.1N NH₃, ampule of 1 mL, certified reference material, Cerilliant^®

• CAS Number: 174418-82-7
• MDL number: MFCD09970594
• UNSPSC Code: 41116107
• PubChem Substance ID: 329815146
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL in methanol with 0.1N NH₃
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: −70°C
• SMILES string: CC[C@@H]1CN2CC[C@@]3(O)C(=Nc4cccc(OC)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC
• InChI: 1S/C23H30N2O5/c1-5-14-12-25-10-9-23(27)20-17(7-6-8-19(20)29-3)24-21(23)18(25)11-15(14)16(13-28-2)22(26)30-4/h6-8,13-15,18,27H,5,9-12H2,1-4H3/b16-13+/t14-,15+,18+,23+/m1/s1
• InChI key: RYENLSMHLCNXJT-CYXFISRXSA-N

Description

General description

Along with mitragynine, 7-Hydroxymitragynine is an active alkaloid found in the plant Mitragynine speciosa, commonly known as Kratom. The compound possesses opioid agonistic activity with a potentcy 30- and 17-fold higher than that of mitragynine and morphine, respectively.

Application

• 7-Hydroxymitragynine research solution for opioid receptor studies: The solution is utilized extensively in opioid receptor agonist research, providing insights into its binding efficacy and downstream effects in neurochemical pathways. This research contributes to understanding opioid-like effects and potential therapeutic uses for pain management and addiction treatment (Zhang et al., 2022).
• Kratom alkaloid standard in bioactive studies: As a bioactive mitragynine derivative, 7-Hydroxymitragynine is employed as a standard in the study of various kratom alkaloids, which aids in elucidating their pharmacological profiles and potential medicinal benefits. This is crucial for developing safe and effective kratom-based treatments (Henningfield et al., 2021).
• Analgesic compound research in pain management: Research on 7-Hydroxymitragynine focuses on its analgesic properties, exploring its effectiveness and safety as a pain-relieving compound. This research is vital for proposing alternatives to traditional opioids, offering potential benefits in terms of reduced side effects and lower addiction risks (Chakraborty et al., 2021).
• High-purity standard for synthetic studies: The high-purity 7-Hydroxymitragynine solution is critical for synthetic and biochemical assays, allowing researchers to study its effects on a molecular level in vitro. This facilitates a deeper understanding of its interaction with biological systems, aiding in the design of targeted pharmacotherapies (Bhowmik et al., 2021).
• Research-grade compound in neurochemistry: Used in neurochemistry to study the effects of kratom extracts and their derivatives, 7-Hydroxymitragynine solution helps delineate its role in altering neurotransmitter release. This research supports the development of novel therapies for disorders characterized by neurotransmitter dysregulation (Zhang et al., 2020).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 35.6 °F - closed cup
• Flash Point(C): 2 °C - closed cup