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KITALYSISBASE

Sigma-Aldrich

KitAlysis High-Throughput Base Screening Kit - Pack of 2

Synonym(s):

Base screen, Base screening kit, KitAlysis base

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About This Item

UNSPSC Code:
12161600
NACRES:
NA.22

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Cross Couplings
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling

functional group

phosphine

Application

Versatile base screening kit for cross-coupling reactions and other synthetic transformations. Step-by-step user guide and a downloadable experimental excel sheet are provided in the below hyperlinks.

Step-by-Step Guide for KitAlysis High-Throughput Base Reaction Screening Kit

Downloadable experimental excel file

Each kit contains 2 customizable screening sets that contain the following:
  • 7 X 2 pre-weighed bases (30 μmol) in individual microvials with magnetic stir bars
  • 4 X 2 base solutions
  • 2 empty microvials for Chemist′s Choice of base allowing customization
  • 4 degassed anhydrous solvents (DMF, MeOH, THF, Toluene)
  • 2 NEW KitAlysis 24-Well Reaction Block Replacement Films
  • 4 empty substrate stock solution reaction vials with stirbars
Monitor reaction progress via TLC-MS by following this protocol

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

Features and Benefits

  • Designed and tested by synthetic chemists
  • Easily run 24-microscale reactions in parallel
  • 10 μmol reactions with 3 equiv. base, 0.1 M concentration
  • Customizable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks

Legal Information

KitAlysis is a trademark of Sigma-Aldrich Co. LLC

Kit Components Only

Product No.
Description

  • Potassium bicarbonate, ACS reagent, 99.7%, powder, crystals or granules

Kit Components Also Available Separately

Product No.
Description
SDS

  • RDD019Potassium phosphate tribasic, anhydrous, free-flowing, Redi-Dri, reagent grade, ≥98%SDS

  • 441902Cesium carbonate, ReagentPlus®, 99%SDS

  • 757551Potassium hydroxide, anhydrous, ≥99.95% trace metals basisSDS

  • 791733Potassium acetate, anhydrous, free-flowing, Redi-Dri, ACS reagent, ≥99.0%SDS

  • 1390091,8-Diazabicyclo[5.4.0]undec-7-ene, 98%SDS

  • 225770Lithium bis(trimethylsilyl)amide solution, 1.0 M in THFSDS

  • 702706Sodium tert-butoxide solution, 2 M in THF, ZerO2®SDS

  • 900522Toluene, anhydrous, ZerO2®, 99.8%SDS

  • 900632Triethylamine, ZerO2®, ≥99%SDS

  • 900636Tetrahydrofuran, anhydrous, inhibitor-free, ZerO2®, ≥99.9%SDS

  • 900638N,N-Dimethylformamide, anhydrous, ZerO2®, 99.8%SDS

  • 900641Methanol, anhydrous, ZerO2®, 99.8%SDS

  • Z118850Spinbar® magnetic stirring fleas, red, L 10 mm, diam. 3 mmSDS

  • Z742110KitAlysis 24-well reaction block replacement filmSDS

  • 900501Potassium carbonate, anhydrous, free-flowing, Redi-Dri, ReagentPlus®, 99%SDS

  • 655104Sodium hydroxide, reagent grade, 97%, powderSDS

See All (16)

Signal Word

Danger

Hazard Statements

Hazard Classifications

Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 2 - STOT RE 2 Oral

Target Organs

Kidney,Adrenal gland,Testes

Supplementary Hazards

Storage Class Code

4.1B - Flammable solid hazardous materials

Flash Point(F)

-5.8 °F

Flash Point(C)

-21 °C


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

KitAlysis High-Throughput Screening Kits provide solution to efficiently identify or optimize suitable catalytic reaction conditions. Chemist can rapidly run 24 unique micro scale reactions in parallel with tailored conditions.

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Chemical reaction design and optimization in organic synthesis aims to precisely alter reaction parameters to achieve optimum results in finding pathways to target molecules.

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