914339

Fmoc-L-Lys(Nvoc)-OH

≥98%

• Synonym(s): (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-6-((4,5-dimethoxy-2-nitrobenzyloxy)carbonylamino)hexanoic acid, N₂-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N₆-(((4,5-dimethoxy-2-nitrobenzyl)oxy)carbonyl)-L-lysine, Lysine with photoremovable NVOC, Photocaged amino acid, Photocleavable lysine derivative
• Empirical Formula (Hill Notation): C₃₁H₃₃N₃O₁₀
• CAS Number: 150571-28-1
• Molecular Weight: 607.61
• MDL number: MFCD08064317
• UNSPSC Code: 12352209
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥98%
• form: powder
• mp: 108 °C (decomp.)
• storage temp.: 2-8°C
• SMILES string: [N+](=O)([O-])c1c(cc(c(c1)OC)OC)COC(=O)NCCCC[C@H](NC(=O)OCC2c3c(cccc3)c4c2cccc4)C(=O)O
• InChI: 1S/C31H33N3O10/c1-41-27-15-19(26(34(39)40)16-28(27)42-2)17-43-30(37)32-14-8-7-13-25(29(35)36)33-31(38)44-18-24-22-11-5-3-9-20(22)21-10-4-6-12-23(21)24/h3-6,9-12,15-16,24-25H,7-8,13-14,17-18H2,1-2H3,(H,32,37)(H,33,38)(H,35,36)/t25-/m0/s1
• InChI key: UOEGMVQGRMCJDM-VWLOTQADSA-N

Description

Application

Fmoc-L-Lys(Nvoc)-OH is a lysine derivative compatible with solid-phase peptide synthesis (SPPS). The photolabile, N-terminal protecting group nitroveratryloxycarbonyl (NVOC) can be cleaved by photolysis at 350 nm. Photocaged amino acids such as these are useful in the synthesis of photocleavable chemical tools for spatial and temporal control over released molecules in biological applications.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Other Notes

Total chemical synthesis of photoactivatable proteins for light-controlled manipulation of antigen-antibody interactions

In situ cell manipulation through enzymatic hydrogel photopatterning

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable