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572616

Sigma-Aldrich

Benzhydryl chloride, polymer-bound

100-200 mesh, extent of labeling: 1.6-2.2 mmol/g loading, 1 % cross-linked with divinylbenzene

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About This Item

MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22

crosslinking

1 % cross-linked with divinylbenzene

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

extent of labeling

1.6-2.2 mmol/g loading

particle size

100-200 mesh

Application

This electrophilic resin is used for the attachment of amines alcohols, sulfamates, thiols and phenols using the Fmoc strategy. This resin is an intermediate between the Merrifield resin and the trityl chloride resin in term of acid lability. The carbocation formed during the cleavage reaction is more stable than Merrifield resin but less stable than the trityl chloride resins. The substituents on the benzhydryl chloride can be chosen in order to obtain a less acid labile resin (2-chloro) or a more acid labile resin (4-Methyl) than the benzhydryl chloride resin.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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