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236527

Sigma-Aldrich

Sodium hydrogencarbonate

ACS reagent, ≥99.7%

Synonym(s):

Sodium bicarbonate

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About This Item

Linear Formula:
NaHCO3
CAS Number:
144-55-8
Molecular Weight:
84.01
Beilstein:
4153970
EC Number:
205-633-8
MDL number:
MFCD00003528
UNSPSC Code:
12352300
PubChem Substance ID:
329752438

grade

ACS reagent

Assay

≥99.7%
99.7-100.3% dry basis

impurities

≤0.003% S compounds
≤0.015% insolubles

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)

density

2.16 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤0.003%
phosphate (PO43-): ≤0.001%

cation traces

Ca, Mg and R2O3 precipitate: ≤0.02%
Fe: ≤0.001%
K: ≤0.005%
NH4+: ≤5 ppm
heavy metals: ≤5 ppm

SMILES string

[Na+].OC([O-])=O

InChI

1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

InChI key

UIIMBOGNXHQVGW-UHFFFAOYSA-M

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
04923PT
15308EI
15222CA
14731KF
13724AO

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Shay P McGuinness et al.
Critical care medicine, 41(7), 1599-1607 (2013-05-21)
Cardiac surgery-associated acute kidney injury occurs in up to 50% of patients and is associated with increased mortality and morbidity. This study aimed to discover if perioperative urinary alkalinization with sodium bicarbonate infusion reduces the prevalence of cardiac surgery-associated acute
Joshua C Tremblay et al.
The Journal of physiology, 593(3), 723-737 (2014-11-25)
Blood flow through intrapulmonary arteriovenous anastomoses (IPAVA) is increased by acute hypoxia during rest by unknown mechanisms. Oral administration of acetazolamide blunts the pulmonary vascular pressure response to acute hypoxia, thus permitting the observation of IPAVA blood flow with minimal
Eric A J Hoste et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 25(3), 747-758 (2009-08-26)
There have been conflicting reports on the use of intravenous administration of sodium bicarbonate for prevention of contrast-induced acute kidney injury (CI-AKI). The aim of this study was to evaluate the use of sodium bicarbonate for prevention of CI-AKI. This
Sophia Zoungas et al.
Annals of internal medicine, 151(9), 631-638 (2009-11-04)
Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN). To determine the effect of sodium bicarbonate on the risk for CIN. MEDLINE, PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials from 1950 to
Nina Dupuis et al.
Human molecular genetics, 24(10), 2771-2783 (2015-02-06)
Dymeclin is a Golgi-associated protein whose deficiency causes Dyggve-Melchior-Clausen syndrome (DMC, MIM #223800), a rare recessively inherited spondyloepimetaphyseal dysplasia consistently associated with postnatal microcephaly and intellectual disability. While the skeletal phenotype of DMC patients has been extensively described, very little
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