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163651

Sigma-Aldrich

Thioacetanilide

98%

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About This Item

Linear Formula:
CH3CSNHC6H5
CAS Number:
Molecular Weight:
151.23
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

form

powder

mp

76-79 °C (lit.)

functional group

amine

SMILES string

CC(=S)Nc1ccccc1

InChI

1S/C8H9NS/c1-7(10)9-8-5-3-2-4-6-8/h2-6H,1H3,(H,9,10)

InChI key

MWCGLTCRJJFXKR-UHFFFAOYSA-N

General description

Metabolism and acute toxicity of thioacetanilide has been studied in rat[1]. Thioacetanilide undergoes nucleophilic addition reaction with superoxide ion in dimethyl sulfoxide[2].

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Reactivity of superoxide ion with thioamides in dimethyl sulfoxide.
Paez OA, et al.
The Journal of Organic Chemistry, 53(10), 2166-2170 (1988)
Li-Rong Wen et al.
The Journal of organic chemistry, 73(5), 1852-1863 (2008-01-29)
A series of unusual fused tricyclic thiochromeno[2,3-b]pyridines were successfully synthesized by tandem [3 + 3] annulation and SNAr of beta-(2-chloroaroyl) thioacetanilides with activated 4-arylidene-2-phenyloxazol-5(4H)-ones or aromatic aldehydes and ethyl 2-cyanoacetate under microwave irradiation, respectively. Because of the existence of the
[Substantiation of maximum permissible levels of thioacylanilide in the air of work areas].
L G Aĭzvert et al.
Gigiena truda i professional'nye zabolevaniia, (7)(7), 51-52 (1986-07-01)
Xiao Li et al.
Bioorganic & medicinal chemistry, 20(18), 5527-5536 (2012-08-14)
In continuation of our efforts toward the discovery of potent HIV-1 NNRTIs with novel structures, we have employed a scaffold hopping strategy to explore the chemically diversed space of bioactive compounds. The original arylazolylthioacetanilide platform was replaced with different imidazopyridinylthioacetanilide
P N Trennery et al.
Xenobiotica; the fate of foreign compounds in biological systems, 13(8), 475-482 (1983-08-01)
The metabolism and acute toxicity of thioacetanilide was studied in the rat. Following intragastric dosage (100 mg/kg), over 90% dose was excreted in urine, predominantly as conjugated metabolites: less than 7% was recovered in the faeces, consisting of unchanged thioacetanilide.

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