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119660

Sigma-Aldrich

Tris(2-chloroethyl) phosphate

97%

Synonym(s):

Phosphoric acid tris(2-chloroethyl) ester

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25 G
₪212.00

About This Item

Linear Formula:
(ClCH2CH2O)3P(O)
CAS Number:
Molecular Weight:
285.49
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

₪212.00


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vapor pressure

<10 mmHg ( 25 °C)

Quality Level

Assay

97%

refractive index

n20/D 1.472 (lit.)

bp

192 °C/10 mmHg (lit.)

solubility

H2O: soluble 7.82 g/L

density

1.39 g/mL at 25 °C (lit.)

SMILES string

ClCCOP(=O)(OCCCl)OCCCl

InChI

1S/C6H12Cl3O4P/c7-1-4-11-14(10,12-5-2-8)13-6-3-9/h1-6H2

InChI key

HQUQLFOMPYWACS-UHFFFAOYSA-N

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General description

Tris(2-chloroethyl) phosphate is used as a flame retardant [1]in plastics, especially inflexible foams used in automobiles and furniture and in rigid foams used for building insulation[2].

Application

Tris(2-chloroethyl) phosphate was used in dynamic air sampling of airborne organophosphate triesters using a solid-phase microextraction device[3].

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

449.6 °F - closed cup

Flash Point(C)

232 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Thorvald Staaf et al.
Journal of environmental monitoring : JEM, 7(9), 883-887 (2005-08-27)
In this study the occurrence of ten organophosphate triesters in indoor air at 29 different locations was investigated. They were detected at all locations and a total of ten compounds were identified. The predominant compounds were the chlorinated compounds tris(chloroisopropyl)
L T Burka et al.
Drug metabolism and disposition: the biological fate of chemicals, 19(2), 443-447 (1991-03-01)
Tris(2-chloroethyl) phosphate (TRCP), a flame retardant, produces a dose-, sex-, and species-dependent lesion in the hippocampal region of the brain following subchronic oral administration. This lesion is more common and more severe in female F344 rats than in male F344
TRIS (2-CHLOROETHYL) PHOSPHATE
IARC Monographs, 71, 1543-1548 (1990)
T Umezu et al.
Toxicology and applied pharmacology, 148(1), 109-116 (1998-02-18)
The present study was conducted to clarify the acute effect of tris(2-chloroethyl)phosphate (TRCP), an organophosphate flame-retardant, on spontaneous ambulatory activity (AA) in male ICR mice and to examine the neurochemical mechanism of this effect. Single dose administration of 200 mg/kg
D W Herr et al.
Drug metabolism and disposition: the biological fate of chemicals, 19(2), 436-442 (1991-03-01)
Tris(2-chloroethyl) phosphate (TRCP) is a flame retardant that has a wide variety of industrial applications. In subchronic studies, oral administration of TRCP to rats and mice has been reported to produce dose-, sex-, and species-dependent lesions in the hippocampal brain

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