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V900580

Sigma-Aldrich

N-Acetyl-L-glutamic acid

Vetec, reagent grade, 99%

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About This Item

Linear Formula:
HO2CCH2CH2CH(NHCOCH3)CO2H
CAS Number:
Molecular Weight:
189.17
Beilstein:
1727473
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:

grade

reagent grade

product line

Vetec

Assay

99%

form

powder or crystals

reaction suitability

reaction type: solution phase peptide synthesis

technique(s)

ligand binding assay: suitable

color

colorless to white

mp

194-196 °C (lit.)

storage temp.

2-8°C

SMILES string

CC(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C7H11NO5/c1-4(9)8-5(7(12)13)2-3-6(10)11/h5H,2-3H2,1H3,(H,8,9)(H,10,11)(H,12,13)/t5-/m0/s1

InChI key

RFMMMVDNIPUKGG-YFKPBYRVSA-N

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Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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M Tuchman et al.
Pediatric research, 27(4 Pt 1), 408-412 (1990-04-01)
N-acetylglutamate (NAG) content was measured in homogenates of liver and small intestine obtained from normal and 24-h starved syngeneic mice. Subsequently, NAG was determined in normal, and in carbamyl phosphate synthetase I and ornithine transcarbamylase enzyme-deficient human liver tissue homogenates.
J Vockley et al.
Biochemical medicine and metabolic biology, 47(1), 38-46 (1992-02-01)
N-Acetyl-L-glutamate synthetase (NAG synthetase) is a mitochondrial matrix enzyme which catalyzes the synthesis of N-acetyl-Lglutamate (NAG), a physiologic activator of the urea cycle enzyme carbamylphosphate synthetase I. Deficiency of NAG synthetase in humans has been reported only three times previously.
W Zhang et al.
Clinical and investigative medicine. Medecine clinique et experimentale, 13(4), 183-188 (1990-08-01)
Liver tissue from 3 patients with carbamyl phosphate synthetase I deficiency and 11 patients with ornithine transcarbamylase deficiency was analyzed by Western blots for the presence of carbamyl phosphate synthetase I and ornithine transcarbamylase cross-reactive material with anti-rat enzyme antibodies.
K Sugahara et al.
Journal of chromatography. B, Biomedical applications, 657(1), 15-21 (1994-07-01)
Liquid chromatography-atmospheric pressure chemical-ionization mass spectrometry (LC-APCI-MS) was used for the analysis of N-acetylamino acids that could not be determined with an amino acid analyzer. LC-APCI-MS could directly detect the protonated molecular ions of various synthetic N-acetylamino acids, distinguishing N-acetylserine
Timothy J Key et al.
The American journal of clinical nutrition, 86(3), 672-681 (2007-09-08)
Previous studies suggest that high plasma concentrations of carotenoids, retinol, or tocopherols may reduce the risk of prostate cancer. We aimed to examine the associations between plasma concentrations of 7 carotenoids, retinol, alpha-tocopherol, and gamma-tocopherol and prostate cancer risk. A

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