FLJ46380 is also known as ring finger protein 207 (RNF207). It is an E3 ligase expressed in the heart. The gene encoding it is located on human chromosome 1p36.31.
Immunogen
FLJ46380 (NP_997279, 135 a.a. ~ 244 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
FLJ46380 or ring finger protein 207 (RNF207) has been studied as a marker for acute myocardial infarction.
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Physical form
Solution in phosphate buffered saline, pH 7.4
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Clinical science (London, England : 1979), 128(11), 751-760 (2015-01-20)
Ubiquitin ligase (E3) is a decisive element of the ubiquitin-proteasome system (UPS), which is the main pathway for intracellular protein turnover. Recently, circulating E3 ligases have been increasingly considered as cancer biomarkers. In the present study, we aimed to determine
QT interval duration, reflecting myocardial repolarization on the electrocardiogram, is a heritable risk factor for sudden cardiac death and drug-induced arrhythmias. We conducted a meta-analysis of three genome-wide association studies in 13,685 individuals of European ancestry from the Framingham Heart
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