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T7392

Sigma-Aldrich

D-(−)-Threose

≥60%, syrup

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About This Item

Empirical Formula (Hill Notation):
C4H8O4
CAS Number:
Molecular Weight:
120.10
Beilstein:
1721696
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
Pricing and availability is not currently available.

form

syrup

Quality Level

optical activity

[α]20/D -16.4 to -9.8 °, c = 2% (w/v) in water

concentration

≥60%

storage temp.

2-8°C

SMILES string

O[C@H]1COC(O)[C@@H]1O

InChI

1S/C4H8O4/c5-2-1-8-4(7)3(2)6/h2-7H,1H2/t2-,3+,4?/m0/s1

InChI key

FMAORJIQYMIRHF-URORKIPUSA-N

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Allen Horhota et al.
Journal of the American Chemical Society, 127(20), 7427-7434 (2005-05-19)
alpha-l-Threofuranosyl nucleoside triphosphates (tNTPs) are tetrafuranose nucleoside derivatives and potential progenitors of present-day beta-d-2'-deoxyribofuranosyl nucleoside triphosphates (dNTPs). Therminator DNA polymerase, a variant of the 9 degrees N DNA polymerase, is an efficient DNA-directed threosyl nucleic acid (TNA) polymerase. Here we
Benjamin D Heuberger et al.
Organic letters, 8(25), 5809-5811 (2006-12-01)
Cytosine TNA promotes nonenzymatic, template-directed oligomerization of complementary activated rGMP, leading to selective and efficient formation of RNA products. This process models "genetic takeover" of a pre-RNA by RNA. [reaction: see text]
Zhenyu Dai et al.
Archives of biochemistry and biophysics, 463(1), 78-88 (2007-05-01)
We isolated a novel acid-labile yellow chromophore from the incubation of lysine, histidine and d-threose and identified its chemical structure by one and two-dimensional NMR spectroscopy combined with LC-tandem mass spectrometry. This new cross-link exhibits a UV absorbance maximum at
María Ruiz et al.
The Journal of organic chemistry, 73(6), 2240-2255 (2008-02-28)
A general strategy for the synthesis of 1-deoxy-azasugars from a chiral glycine equivalent and 4-carbon building blocks is described. Diastereoselective aldol additions of metalated bislactim ethers to matched and mismatched erythrose or threose acetonides and intramolecular N-alkylation (by reductive amination
Veerle Kempeneers et al.
Chemistry & biodiversity, 1(1), 112-123 (2006-12-29)
TNA (alpha-L-threose nucleic acids) is potentially a natural nucleic acid, that might have acted as an evolutionary alternative of RNA. We determined the catalytic activity of hammerhead ribozymes containing a threofuranosyl-modified nucleoside at position U4 and U7, and compared these

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