SRP6305

Lactalbumin from human milk

≥95% (SDS-PAGE)

• Synonym(s): LYZL7
• UNSPSC Code: 12352202
• NACRES: NA.32

Properties

• biological source: human milk
• Assay: ≥95% (SDS-PAGE)
• form: lyophilized
• mol wt: 14 kDa
• packaging: pkg of 5 mg
• UniProt accession no.: P00709
• shipped in: wet ice
• storage temp.: 2-8°C
• Gene Information: human ... LYZL7(3906)

Description

General description

α-Lactalbumin is an important whey protein in cow′s milk, and is also present in the milk of many other mammalian species. In primates, α-lactalbumin expression is upregulated in response to the hormone prolactin and increases the production of lactose. α-Lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and β-1,4-galactosyltransferase (β4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transferring galactose moieties to glucose. As a monomer, α-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. When formed into a complex with Gal-T1, a galactosyltransferase, α-lactalbumin, enhances the enzyme′s affinity for glucose by about 1000 times, and inhibits the ability to polymerize multiple galactose units. This gives rise to a pathway for forming lactose by converting Gal-TI to Lactose synthase.

Physical form

Lyophilized from de-ionized water.

Reconstitution

Use deionized water

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable