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Key Documents

SAB4503045

Sigma-Aldrich

Anti-Tubulin γ, C-Terminal antibody produced in rabbit

affinity isolated antibody

Synonym(s):

γ-1-tubulin, γ-tubulin complex component 1, GCP-1, TUBG1, Tubulin γ-1 chain

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 51 kDa

species reactivity

mouse, rat, human

concentration

~1 mg/mL

technique(s)

ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI accession no.

P23258

UniProt accession no.

P23258

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TUBG1(7283)

General description

Anti-Tubulin γ Antibody detects endogenous levels of total Tubulin γ protein.
TUBG1 (tubulin γ) gene is mapped to human chromosome 17q21.2. It is ubiquitously expressed but predominantly expressed in fetal neurons. It is considered to be highly conserved. Tubulin γ is localized at the microtubule organizing centers and spindle fibres during mitosis.

Immunogen

The antiserum was produced against synthesized peptide derived from human Tubulin gamma.

Immunogen Range: 386-435

Application

Anti-Tubulin γ, C-Terminal antibody produced in rabbit has been used in immunofluorscence.

Biochem/physiol Actions

Tubulin γ is involved in mitotic microtubule organization and nucleation.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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SOX2 Drives Bronchial Dysplasia in a Novel Organotypic Model of Early Human Squamous Lung Cancer.
American Journal of Respiratory and Critical Care Medicine, 195(11), 1494-1508 (2017)
Molecular insight into ?-? tubulin lateral interactions within the ?-tubulin ring complex (?-TuRC)
Suri C
Journal of Computer-Aided Molecular Design, 28(9), 961-972 (2014)
Eukaryotic operon genes can define highly conserved syntenies.
Trachtulec Z
Current Opinion in Genetics & Development, 50(1), 1-6 (2004)
Differential expression of human ?-tubulin isotypes during neuronal development and oxidative stress points to a ?-tubulin-2 prosurvival function.
Draberova E
Faseb Journal, 31(5), 1828-1846 (2017)
Kerstin Hasenpusch-Theil et al.
eLife, 9 (2020-08-26)
During the development of the cerebral cortex, neurons are generated directly from radial glial cells or indirectly via basal progenitors. The balance between these division modes determines the number and types of neurons formed in the cortex thereby affecting cortical
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