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SAB4300168

Sigma-Aldrich

Anti-phospho-SYT1 (pSer309) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-DKFZp781D2042 antibody produced in rabbit, Anti-P65 antibody produced in rabbit, Anti-SVP65 antibody produced in rabbit, Anti-SYT antibody produced in rabbit, Anti-synaptotagmin I antibody produced in rabbit

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100 μG
€371.00

€371.00


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100 μG
€371.00

About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

€371.00


Please contact Customer Service for Availability

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~46 kDa

species reactivity

human, rat, mouse

concentration

1 mg/mL

technique(s)

indirect immunofluorescence: 1:100-1:200

isotype

IgG

immunogen sequence

(G-L-SP-D-P)

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer309)

Gene Information

human ... SYT1(6857)

Immunogen

Peptide sequence around phosphorylation site of serine 309 (G-L-S(p)-D-P), according to the protein SYT1.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Target description

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Juan Hu et al.
European journal of pharmacology, 857, 172449-172449 (2019-06-18)
Endoplasmic reticulum stress (ERS)-induced cardiomyocyte apoptosis plays an important role in the pathological process following myocardial infarction (MI). Macrophages that express microRNA-155 (miR-155) mediate cardiac inflammation, fibrosis, and hypertrophy. Therefore, we investigated if miR-155 regulates ERS-induced cardiomyocyte apoptosis after MI
Juan Hu et al.
European journal of pharmacology, 851, 122-132 (2019-02-06)
Inflammation plays an important role in sympathetic neural remodeling induced by myocardial infarction (MI). MiR-155 is a vital regulator of inflammatory responses, and macrophage-secreted miR-155 promotes cardiac fibrosis and hypertrophy. However, whether miR-155 influences MI-induced sympathetic neural remodeling is not
Papa Diogop Ndiaye et al.
Theranostics, 9(3), 661-675 (2019-02-28)
Hypoxic zones are common features of metastatic tumors. Due to inactivation of the von Hippel-Lindau gene (VHL), renal cell carcinomas (RCC) show constitutive stabilization of the alpha subunit of the hypoxia-inducible factor (HIF). Thus, RCC represents a model of chronic
Chang Liu et al.
Journal of immunology (Baltimore, Md. : 1950), 202(10), 2957-2970 (2019-04-07)
MAVS is a critical adaptor required for activating an innate antiviral immune response against viral infection. The activation of MAVS requires modification of the Lys63-linked ubiquitination and formation of prion-like aggregates. However, the molecular mechanisms regulating MAVS activity remain largely
Chun Chen et al.
Cell death & disease, 10(3), 178-178 (2019-02-23)
The mechanisms underlying the role of CXCL5 in tumor angiogenesis have not been fully defined. Here, we examined the effect of CXCL5 on tumor angiogenesis in colorectal cancer (CRC). Immunohistochemistry was used to monitor the expression of CXCL5 and CD31

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