SAB2500273

Anti-CRHR1/CRF-R (AA 250-263) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-CRF-R, Anti-CRF1, Anti-CRH-R1h, Anti-Corticotropin releasing hormone receptor 1
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: goat
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): immunohistochemistry: suitable; indirect ELISA: suitable; indirect immunofluorescence: suitable
• UniProt accession no.: P34998
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... CRHR1(1394)

Description

General description

Corticotropin releasing factor receptor 1 (CRHR1) belongs to the G-protein-coupled receptor superfamily of brain-gut neuropeptides. It is highly expressed in the amygdala, hippocampus and frontal cortex. The gene encoding CRHR1 consists of 13 exons and is localized on human chromosome 17q12-q22.

Immunogen

Peptide with sequence KLYYDNEKCWFGKR from the internal region of the protein sequence according to NP_004373.2.

Biochem/physiol Actions

Corticotropin releasing factor receptor 1 (CRHR1) helps to initiate signal transduction pathways that control various functions like stress, reproduction, immune response and obesity. It blocks the multiplication of endocrine-related cancer cell lines.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319
• Precautionary Statements: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable