This product is not a sterile preparation. If the intended use, such as in cell culture, requires a sterile environment, then the stock solution would require filter sterilization. Typically, this is achieved by filtration through a 0.22 um membrane. Alternatively, product S9133 is a γ-irradiated, sterile powder. When reconstituted aseptically using sterile water, this product may be added directly to culture medium.
Please see the link below to review this product option:
https://www.sigmaaldrich.com/product/sigma/s9133
S5261
Sodium selenite
BioReagent, suitable for cell culture, ≥98%
Synonym(s):
Selenious acid, Sodium salt
Sign Into View Organizational & Contract Pricing
Select a Size
10 G
€63.50
25 G
€128.00
100 G
€257.00
All Photos(3)
Select a Size
Change View
10 G
€63.50
25 G
€128.00
100 G
€257.00
About This Item
Linear Formula:
Na2SeO3
CAS Number:
Molecular Weight:
172.94
EC Number:
MDL number:
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.75
Recommended Products
biological source
synthetic (inorganic)
Quality Level
product line
BioReagent
Assay
≥98%
form
powder
technique(s)
cell culture | mammalian: suitable
mp
>350 °C (lit.)
solubility
water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
SMILES string
[Na+].[Na+].[O-][Se]([O-])=O
InChI
1S/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2
InChI key
BVTBRVFYZUCAKH-UHFFFAOYSA-L
Looking for similar products? Visit Product Comparison Guide
Application
Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
Supplementary Hazards
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Astrocytes expressing ALS-linked mutant FUS induce motor neuron death through release of tumor necrosis factor-alpha
Kia A, et al.
Glia, 66(5), 1016-1033 (2018)
Canonical TGF-beta signaling negatively regulates neuronal morphogenesis through TGIF/Smad complex-mediated CRMP2 suppression
Nakashima H, et al.
The Journal of Neuroscience, 2423-2417 (2018)
Miao Zhang et al.
Stem cells (Dayton, Ohio), 33(5), 1456-1469 (2015-02-03)
Directed cardiac differentiation of human pluripotent stem cells (hPSCs) enables disease modeling, investigation of human cardiogenesis, as well as large-scale production of cardiomyocytes (CMs) for translational purposes. Multiple CM differentiation protocols have been developed to individually address specific requirements of
Simon P W Hageman et al.
Water research, 47(7), 2118-2128 (2013-03-15)
Removal of the toxic selenium compounds selenite and selenate from waste water before discharge is becoming increasingly imperative in industrialized countries. Bacteria can reduce selenate to selenite, but also further to elemental selenium, selenide or organic selenium. In this paper
Chih-Ching Yang et al.
PloS one, 9(7), e96006-e96006 (2014-07-02)
Deep-sea water (DSW), which is rich in micronutrients and minerals and with antioxidant and anti-inflammatory qualities, may be developed as marine drugs to provide intestinal protection against duodenal ulcers. We determined several characteristics in the modified DSW. We explored duodenal
Articles
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
-
need filtration (0.2um) after preparation?
1 answer-
Helpful?
-
-
How long does an aliquot of this product in water remain stable at -20 degrees Celsius?
1 answer-
As mentioned on the Product Datasheet, stock solutions of sodium selenite may be frozen. Working aliquots remain active for 30 days at 2-8 °C. The Datasheet can accessed in the DOCUMENTATION section under 'More Documents'. Please see the link below:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/245/224/s5261pis.pdfHelpful?
-
-
What solvent do I need to use? DMSO OK?
1 answer-
This item is soluble in water at 50mg/mL. The solubility in DMSO as not been tested.
Helpful?
-
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
