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L3750

Sigma-Aldrich

β-Lactose

≤30% α-anomer basis, ≥99% total lactose basis

Synonym(s):

β-D-Gal-(1→4)-β-D-Glc

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100 G
€119.00
500 G
€336.00
1 KG
€623.00

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100 G
€119.00
500 G
€336.00
1 KG
€623.00

About This Item

Empirical Formula (Hill Notation):
C12H22O11
CAS Number:
5965-66-2
Molecular Weight:
342.30
EC Number:
227-751-9
MDL number:
MFCD00064521
UNSPSC Code:
12352201
PubChem Substance ID:
24896352
NACRES:
NA.25

€119.00

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biological source

bovine milk

Assay

≥99% total lactose basis

form

powder

concentration

≥30% (α-anomer)

color

white to off-white

solubility

water: 50 mg/mL, clear, colorless

storage temp.

room temp

SMILES string

OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11-,12+/m1/s1

InChI key

GUBGYTABKSRVRQ-DCSYEGIMSA-N

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General description

Lactose is an important disaccharide in human nutrition, culinary goods, and pharmaceuticals. β-lactose is an isomeric form that is rarely found in nature.[1]

Application

β-Lactose has been used:
  • to treat HL-1 cells followed by phorbol dibutyrate (PDB) treatment to study if protein kinase C (PKC) -stimulated accumulation is mediated through galectin-3[2]
  • as a component of a media to analyze the extracellular production of protein[3]
  • along with recombinant galectin-3 to treat cells for the detection of galectin-3 cell surface binding[4]
  • along with recombinant galectin-3 or a control protein to stimulate T cells for apoptosis assay[4]

Biochem/physiol Actions

Beta-Lactose is the beta-pyranose form of the compound lactose.
Lactose, an excipient in a various medication, is used as an additive in a variety of foods. It is utilized as a commercial additive in the food industry due to its texture, flavor, and adhesive characteristics.[1]

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000437235
0000437235
0000437234
0000437234
0000366777

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Benjamin D Grant et al.
Analytical chemistry, 92(16), 11305-11309 (2020-07-02)
The SARS-CoV-2 pandemic has created an unprecedented need for rapid diagnostic testing to enable the efficient treatment and mitigation of COVID-19. The primary diagnostic tool currently employed is reverse transcription polymerase chain reaction (RT-PCR), which can have good sensitivity and
A tool for monitoring Trichoderma harzianum: I. Transformation with the GUS gene by protoplast technology
Thrane C, et al.
Phytopathology, 85(11), 1428-1435 (1995)
Detlef Ritter et al.
Toxicology in vitro : an international journal published in association with BIBRA, 63, 104714-104714 (2019-11-11)
Due to the increasing need of new treatment options against bacterial lung infections, novel antimicrobial peptides (AMPs) are under development. Local bioavailability and less systemic exposure lead to the inhalation route of administration. Combining AMPs with nanocarriers (NCs) into nanosystems
Preparation and characterization of high purity anhydrous beta-Lactose from alpha-Lactose monohydrate at mild temperature
Lopez-Pablos AL, et al.
International Journal of Polymer Science (2018)
Logan K Smith et al.
eLife, 10 (2021-08-10)
Despite the mechanisms of central and peripheral tolerance, the mature B cell compartment contains cells reactive for self-antigen. How these cells are poised not to respond and the mechanisms that restrain B cell responses to low-affinity endogenous antigens are not
View All Related Papers

Questions

1–3 of 3 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. Is there a milled lactose product available with a particle size specification of 50 microns or less?

    1 answer

    1. it is noted that there are several lactose products available, but none of them have a size specification of less than 50 microns or 350 mesh. The product specifications primarily indicate that the product should appear in powder or crystal form. None of the available lactose products meet the criteria to be described as milled

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