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H0379

Sigma-Aldrich

19-Hydroxy-4-androstene-3,17-dione

Synonym(s):

4-Androsten-19-ol-3,17-dione, 4-Androstene-3,17-dione-19-ol

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About This Item

Empirical Formula (Hill Notation):
C19H26O3
CAS Number:
510-64-5
Molecular Weight:
302.41
Beilstein:
2567249
EC Number:
208-116-5
MDL number:
MFCD00003616
UNSPSC Code:
12352200
PubChem Substance ID:
24895398
Pricing and availability is not currently available.

SMILES string

C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34CO)[C@@H]1CCC2=O

InChI

1S/C19H26O3/c1-18-8-7-16-14(15(18)4-5-17(18)22)3-2-12-10-13(21)6-9-19(12,16)11-20/h10,14-16,20H,2-9,11H2,1H3/t14-,15-,16-,18-,19+/m0/s1

InChI key

XGUHPTGEXRHMQQ-BGJMDTOESA-N

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Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H361

Precautionary Statements

P281

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
090K4126
046H4031
115F4013

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[Hypertensinogenic steroid].
M Soma et al.
Nihon rinsho. Japanese journal of clinical medicine, 47(9), 2104-2108 (1989-09-01)
J P Weniger et al.
Reproduction, nutrition, development, 30(2), 253-257 (1990-01-01)
Aromatase activity in the foetal rat testis was demonstrated by the conversion of [3H] testosterone into oestradiol. However, the conversion rate was low, around 0.06%, probably because the radioactive precursor was heavily diluted by the large amounts of endogenous testosterone
H Sekihara et al.
The Journal of endocrinology, 138(1), 31-40 (1993-07-01)
We have reported that 19-hydroxyandrostenedione (19-OH-A-dione) amplifies the sodium-retaining action of aldosterone. To evaluate whether it also amplifies the hypertensive action of small doses of aldosterone, mononephrectomized rats were given 0.5 mg aldosterone, 10 mg 19-OH-A-dione or a combination of
D J McRobie et al.
The Journal of steroid biochemistry and molecular biology, 63(1-3), 147-153 (1998-02-04)
Diabetes complicates 2-3% of all pregnancies and is associated with an increase in both perinatal morbidity and mortality, though reasons for these adverse outcomes are unknown. Estrogen biosynthesis is a critical factor during pregnancy and is carried out in the
H Murase et al.
The Journal of steroid biochemistry and molecular biology, 38(3), 331-337 (1991-03-01)
To verify the aldosterone amplifying action of 19-hydroxyandrostenedione (19-OH-AD), we investigated [3H]aldosterone and [3H]19-OH-AD binding to type I (mineralocorticoid) receptor in the renal cytosol of adrenalectomized and ovariectomized rat, and human mononuclear leucocytes (MNL). In the [3H]aldosterone binding study, the
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