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Key Documents

F1642

Sigma-Aldrich

Flurandrenolide

Synonym(s):

6α-Fluoro-11β,16α,17,21-tetrahydroxypregn-4-ene-3,20-dione 16,17-acetonide, Fludroxycortide

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About This Item

Empirical Formula (Hill Notation):
C24H33FO6
CAS Number:
Molecular Weight:
436.51
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

SMILES string

CC1(C)O[C@@H]2CC3C4C[C@H](F)C5=CC(=O)CCC5(C)C4C(O)CC3(C)[C@@]2(O1)C(=O)CO

InChI

1S/C24H33FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h7,13-14,16-17,19-20,26,28H,5-6,8-11H2,1-4H3/t13?,14?,16-,17?,19+,20?,22?,23?,24+/m0/s1

InChI key

POPFMWWJOGLOIF-CCRGDLLISA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Perianal comedones associated with chronic topical fluorinated steroid use.
E J Oliet et al.
Journal of the American Academy of Dermatology, 7(3), 405-407 (1982-09-01)
[Adverse effects of topical steroid preparations].
M Kibler-Nockowska
Polski tygodnik lekarski (Warsaw, Poland : 1960), 35(14), 505-507 (1980-04-07)
G E Rauscher et al.
Cutis, 37(1), 67-68 (1986-01-01)
The use of complete surgical excision and postoperative pressure with steroid-impregnated tape has been evaluated in fifty-seven patients with recurrent earlobe keloids. All patients underwent conventional treatment previously, which was not curative. In a four-year follow-up of the method described
D V Stevanovic et al.
The British journal of dermatology, 96(1), 67-70 (1977-01-01)
Clobetasone butyrate ointment has been shown to be more effective in treating psoriasis and eczema than flurandrenolone ointment yet to cause less epidermal thinning in a human experimental model. This is an indication that the clinical activity of topical glucocorticoids
Pustular psoriasis following treatment of rheumatoid arthritis with TNF-alpha inhibitors.
Genevieve Egnatios et al.
Journal of drugs in dermatology : JDD, 7(10), 975-977 (2008-12-31)

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