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AV49916

Sigma-Aldrich

Anti-LRRC8E antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-FLJ23420, Anti-Leucine-rich repeat containing 8 family, member E

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100 μL
€381.00

€381.00

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100 μL
€381.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

€381.00

Please contact Customer Service for Availability

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

62 kDa

species reactivity

horse, dog, human, guinea pig, bovine, rabbit, mouse, rat

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_079337

UniProt accession no.

Q6NSJ5

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... LRRC8E(80131)

Immunogen

Synthetic peptide directed towards the middle region of human LRRC8E

Application

Anti-LRRC8E antibody produced in rabbit is suitable for western blotting at a concentration of 0.5μg/ml.

Biochem/physiol Actions

Leucine rich repeat containing 8 family, member E (LRRC8E) is involved in proliferation and activation of lymphocytes and monocytes.

Sequence

Synthetic peptide located within the following region: LRELKQLKVLSLRSNAGKVPASVTDVAGHLQRLSLHNDGARLVALNSLKK

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
QC21618

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Keiko Kubota et al.
FEBS letters, 564(1-2), 147-152 (2004-04-20)
In a previous study, we isolated a novel gene, LRRC8 (leucine-rich repeat-containing 8), in a girl with congenital agammaglobulinemia. We have now identified four unknown LRRC8-like genes, named TA-LRRP, AD158, LRRC5, and FLJ23420. Their predicted structures are very similar to

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