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Sigma-Aldrich

Aluminum chloride hexahydrate

Aluminum chloride hexahydrate

ReagentPlus®, 99%

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100 G
€35.80
500 G
€102.00

€35.80


Estimated to ship on18 February 2025Details


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100 G
€35.80
500 G
€102.00

About This Item

Empirical Formula (Hill Notation):
AlCl3 · 6H2O
CAS Number:
Molecular Weight:
241.43
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.55
Assay:
99%
form:
crystalline solid
crystals or chunks

€35.80


Estimated to ship on18 February 2025Details


Request a Bulk Order

vapor pressure

1 mmHg ( 100 °C)

Quality Level

product line

ReagentPlus®

Assay

99%

form

crystalline solid
crystals or chunks

reaction suitability

reagent type: catalyst
core: aluminum

pH

2.5-3.5 (20 °C)

SMILES string

Cl[Al](Cl)Cl.O.O.O.O.O.O

InChI

1S/Al.3ClH.6H2O/h;3*1H;6*1H2/q+3;;;;;;;;;/p-3

InChI key

JGDITNMASUZKPW-UHFFFAOYSA-K

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General description

Aluminum chloride hexahydrate is a nonflammable compound widely employed as a catalyst in organic synthesis. In addition to being extremely soluble in water, it is also soluble in alcohol, ether, glycerol, propylene glycol, and acetonitrile. It has many uses, including the refinement of crude oil, the production of deodorants and antiperspirant products, the dyeing of fabrics, textile finishing.

Application

Aluminum chloride hexahydrate is used as a catalyst:
  • In the synthesis of corresponding THP (tetrahydropyranylation) ether from alcohol or phenol, and 3,4-dihydro-2H-pyran (DHP).
  • In the direct esterification of levulinic acid and ethanol to produce ethyl levulinate.
  • In the synthesis of gem-dihydroperoxides from ketones and aldehydes.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazardCorrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B - STOT RE 1

Target Organs

Lungs

Supplementary Hazards

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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[Axillary hyperhydrosis. Local treatment with 25% aluminum chloride hexahydrate in absolute alcohol].
F Brandrup et al.
Ugeskrift for laeger, 140(35), 2106-2109 (1978-08-28)
Ingrid Siemund et al.
Contact dermatitis, 77(5), 288-296 (2017-07-12)
Contact allergy to aluminium has been reported more frequently in recent years. It has been pointed out that positive patch test reactions to aluminium may not be reproducible on retesting. To investigate possible variations in patch test reactivity to aluminium
Mark Baranov et al.
Inorganic chemistry, 58(13), 8877-8883 (2019-06-30)
While sophisticated computational methods can predict 31P NMR spectra of phosphorus atoms encapsulated within Keggin-derived heteropoly tungstate and molybdate cluster anions, calculated and experimental chemical shift values typically deviate considerably from one another. Motivated by the observation that experimentally determined
Aluminium (III) chloride hexahydrate: an efficient and versatile reagent in organic synthesis.
Sarma SD, et al.
ARKIVOC (Gainesville, FL, United States), 1, 243-263 (2013)
C L Goh
International journal of dermatology, 29(5), 368-370 (1990-06-01)
The efficacy of topical aluminium chloride hexahydrate 20% W/W ethanol (ACH) in the treatment symptomatic palmar hyperhidrosis was studied in 12 patients. A half-sided control single blind (assessor blind) study was done. Patients applied ACH on one palm daily for

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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