PHL89600

Chelidonine

phyproof^® Reference Substance

• Synonym(s): Stylophorin
• Empirical Formula (Hill Notation): C₂₀H₁₉NO₅
• CAS Number: 476-32-4
• Molecular Weight: 353.37
• EC Number: 207-504-1
• MDL number: MFCD00069660
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: primary reference standard
• product line: phyproof^® Reference Substance
• Assay: ≥95.0% (HPLC)
• manufacturer/tradename: PhytoLab
• application(s): food and beverages
• format: neat
• storage temp.: 2-8°C
• SMILES string: [H][C@]12[C@@H](O)Cc3cc4OCOc4cc3[C@@]1([H])N(C)Cc5c6OCOc6ccc25
• InChI: 1S/C20H19NO5/c1-21-7-13-11(2-3-15-20(13)26-9-23-15)18-14(22)4-10-5-16-17(25-8-24-16)6-12(10)19(18)21/h2-3,5-6,14,18-19,22H,4,7-9H2,1H3/t14-,18-,19+/m0/s1
• InChI key: GHKISGDRQRSCII-ZOCIIQOWSA-N

Description

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Inhibits tubulin polymerisation (IC₅₀=24 μM), thereby disrupting microtubule structure in cells and inducing a G2/M mitotic arrest.

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301 + H331
• Precautionary Statements: P261 - P264 - P271 - P301 + P310 - P304 + P340 + P311 - P403 + P233
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable