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6-Chloropyridine-3-carboxylic acid

PESTANAL®, analytical standard

Synonym(s):

6-Chloronicotinic acid

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About This Item

Empirical Formula (Hill Notation):
C6H4ClNO2
CAS Number:
Molecular Weight:
157.55
Beilstein:
115993
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

Assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

185-190 °C
190 °C (dec.) (lit.)

application(s)

agriculture
environmental

format

neat

SMILES string

OC(=O)c1ccc(Cl)nc1

InChI

1S/C6H4ClNO2/c7-5-2-1-4(3-8-5)6(9)10/h1-3H,(H,9,10)

InChI key

UAWMVMPAYRWUFX-UHFFFAOYSA-N

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General description

6-Chloropyridine-3-carboxylic acid is a metabolite of the neonicotinoid pesticides, imidacloprid and acetamiprid and occurs in different environmental matrices.(3) It is widely used in agricultural crop protection, domestic insect control and environmental pest management.
Find more information here: Neonicotinoids

Application

6-Chloropyridine-3-carboxylic acid may be used as an analytical reference standard for the quantification of the analyte in biological samples and animal derived foods using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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A green HPLC technique with a 100\% water mobile phase for detecting imidacloprid and its metabolite 6-chloronicotinic acid
Furusawa N
Current Chemistry Letters, 5(1), 27-32 (2016)
Qualitative profiling and quantification of neonicotinoid metabolites in human urine by liquid chromatography coupled with mass spectrometry
Taira K, et al.
Testing, 8(11) (2013)
Qualitative profiling and quantification of neonicotinoid metabolites in human urine by liquid chromatography coupled with mass spectrometry
Taira K, et al.
PLoS ONE, 8(11) (2013)
A Segura Carretero et al.
Journal of chromatography. A, 1003(1-2), 189-195 (2003-08-06)
A method is described for the analysis of the insecticide imidacloprid [1-(6-chloro-3-pyridylmethyl)-N-nitroimidazolidin-2-ylideneamine] and its metabolite 6-chloronicotinic acid by micellar electrokinetic chromatography with diode-array detection at 270 and 227 nm, respectively. The best results were obtained using sodium dodecyl sulphate at
Mehmet Karabacak et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 71(3), 876-883 (2008-03-25)
The experimental and theoretical study on the structures and vibrations of 6-chloronicotinic acid (6-CNA, C(6)H(4)ClNO(2)) are presented. The Fourier transform infrared spectra (4,000-50 cm(-1)) and the Fourier transform Raman spectra (3,500-50 cm(-1)) of the title molecule in solid phase have

Protocols

Learn more about Neonicotinoids - active substances used in plant protection products to control harmful insects.

Analysis of banned neonicotinoid insecticides from dandelion blossoms using QuEChERS and LC-MS.

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