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Arsenic(III) oxide

reference material for titrimetry, certified by BAM, >99.5%

Synonym(s):

Arsenic trioxide, Arsenous acid

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About This Item

Empirical Formula (Hill Notation):
As2O3
CAS Number:
1327-53-3
Molecular Weight:
197.84
EC Number:
215-481-4
MDL number:
MFCD00003433
UNSPSC Code:
41116107
eCl@ss:
38080102
PubChem Substance ID:
329751594
NACRES:
NA.24

grade

reference material

Quality Level

100

Assay

>99.5%

quality

certified by BAM

technique(s)

titration: suitable

application(s)

agriculture
environmental

format

neat

SMILES string

O=[As]O[As]=O

InChI

1S/As2O3/c3-1-5-2-4

InChI key

IKWTVSLWAPBBKU-UHFFFAOYSA-N

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General description

Arsenic(III) oxide is a volumetric standard produced under rigorous conditions and measured with the highest possible precision. Its content determination and homogeneity assessment are carried out using volumetric redox titration as the primary analysis method.

Application

The reference material is to be used as a reductometric standard for titer determinations in redox titrations.

Features and Benefits

  • Available as a solid in a secure glass bottle to ensure its stability for the entire shelf life until opened.
  • Traceable to NIST standard reference material
  • Offers accurate titer determinations
  • Accompanied by a certificate of analysis (CoA)

Analysis Note

Exact concentration, expiry date and detailed information on certification can be found on the certificate and certification report, included in each package. Content and expiry date on label.

Signal Word

Danger

Hazard Statements

H300,H314,H350,H372,H410

Hazard Classifications

Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1

Target Organs

Respiratory system,Cardio-vascular system,Gastrointestinal tract

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH SVHC Candidate List

CAS No.

EU REACH Annex XVII (Restriction List)

CAS No.

EU REACH Annex XIV (Authorisation List)

CAS No.

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ8820
BCCB5135
BCCB3431
BCBT8539
BCBM3195V

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Michael Ash, Irene Ash
Handbook of Preservatives, 281 -281 (2004)
Arsenic?glutathione complexes?their stability in solution and during separation by different HPLC modes.
Raab, Andrea, et al.
Journal of Analytical Atomic Spectrometry, 19.1, 183-190 (2004)
Ling-Huei Yih et al.
Toxicology and applied pharmacology, 267(3), 228-237 (2013-01-29)
Accumulated evidence has revealed a tight link between arsenic trioxide (ATO)-induced apoptosis and mitotic arrest in cancer cells. AKT, a serine/threonine kinase frequently over-activated in diverse tumors, plays critical roles in stimulating cell cycle progression, abrogating cell cycle checkpoints, suppressing
Cui Li et al.
Toxicology letters, 219(3), 223-230 (2013-04-02)
Arsenic trioxide (As2O3; ATO) is clinically effective in treating acute promyelocytic leukemia (APL); however, it frequently causes cardiotoxic effects. This study was designed to investigate whether ATO could induce apoptosis of cardiac fibroblasts (CFs) that play very important roles in
Athena Kritharis et al.
Annals of hematology, 92(6), 719-730 (2013-03-16)
For more than 2,000 years, arsenic and its derivatives have shown medical utility. Owing to the toxicities and potential carcinogenicity of arsenicals, their popularity has fluctuated. The exact mechanism of action of therapeutic arsenic is not well characterized but likely
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