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30-1940

Sigma-Aldrich

Thiourea

JIS special grade, ≥98.0%

Synonym(s):

Sulfourea, Thiocarbamide

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About This Item

Linear Formula:
NH2CSNH2
CAS Number:
62-56-6
Molecular Weight:
76.12
Beilstein:
605327
MDL number:
MFCD00008067
UNSPSC Code:
12352300
PubChem Substance ID:
329753346

grade

JIS special grade

Assay

≥98.0%

form

solid

availability

available only in Japan

mp

170-176 °C (lit.)

SMILES string

NC(N)=S

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

InChI key

UMGDCJDMYOKAJW-UHFFFAOYSA-N

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Application

Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins

Signal Word

Warning

Hazard Statements

H302,H351,H361fd,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yoshiji Takemoto
Chemical & pharmaceutical bulletin, 58(5), 593-601 (2010-05-13)
We have developed several multifunctional thiourea catalysts bearing a tertiary amine or an 1,2-amino alcohol in expectation of their synchronous activation of a nucleophile and an electrophile through both acid-base and hydrogen-bonding interactions. From these studies, it was revealed that
Ai-Fang Li et al.
Chemical Society reviews, 39(10), 3729-3745 (2010-08-26)
This critical review highlights recent advances in the structurally modified (thio)urea-based receptors for anion complexation and sensing. Modifications of the (thio)urea structure are aimed at a better anion binding in terms of higher binding constant, anion selectivity and feasibility. Major
Iris Keren et al.
Science (New York, N.Y.), 339(6124), 1213-1216 (2013-03-09)
Bactericidal antibiotics kill by modulating their respective targets. This traditional view has been challenged by studies that propose an alternative, unified mechanism of killing, whereby toxic reactive oxygen species (ROS) are produced in the presence of antibiotics. We found no
Elaine M Boyle et al.
The Journal of organic chemistry, 78(17), 8312-8319 (2013-08-01)
Thiourea-functionalized Tröger's base receptors 1 and 2 have been synthesized and evaluated as novel for the recognition of anions. Receptor 2 gave rise to significant changes in the absorption spectrum upon titration with AcO(-) and H2PO4(-) and acted as a
David Weisbrod et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(18), E1685-E1694 (2013-04-17)
Proper expression and function of the cardiac pacemaker is a critical feature of heart physiology. Two main mechanisms have been proposed: (i) the "voltage-clock," where the hyperpolarization-activated funny current If causes diastolic depolarization that triggers action potential cycling; and (ii)
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