Synthetic peptide from rat gamma4 calcium channel.
Application
Anti-Calcium Channel Antibody, γ 4 detects level of Calcium Channel & has been published & validated for use in WB.
Immunoblotting: 5-10 μg/mL. Reacts with the 36.5 kD protein.
Optimal working dilutions must be determined by the end user.
Research Category Neuroscience
Research Sub Category Ion Channels & Transporters
Signaling Neuroscience
Physical form
Format: Purified
Purified immunoglobulin. Liquid in PBS containing 0.08% sodium azide.
Storage and Stability
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Analysis Note
Control Rat brain lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Alterations in AMPA receptor subunits and TARPs in the rat nucleus accumbens related to the formation of Ca??-permeable AMPA receptors during the incubation of cocaine craving.
Ferrario, CR; Loweth, JA; Milovanovic, M; Ford, KA; Gali?anes, GL; Heng, LJ; Tseng, KY; Wolf, ME
Behavioral sensitization to cocaine is associated with increased AMPA receptor (AMPAR) surface expression in the nucleus accumbens (NAc). This upregulation is withdrawal-dependent, as it is not detected on withdrawal day (WD) 1, but is observed on WD7-21. Its underlying mechanisms
We characterized the distribution of AMPA receptor (AMPAR) subunits and the transmembrane AMPA receptor regulatory proteins (TARPs) γ-2 and γ-4 in adult rat nucleus accumbens (NAc) using a method that separates plasma membranes into synaptic membrane-enriched and extrasynaptic membrane-enriched fractions.
Alcoholism, clinical and experimental research, 38(11), 2800-2808 (2014-11-26)
The long-term consequences of adolescent alcohol abuse that persist into adulthood are poorly understood and have not been widely investigated. We have shown that intermittent exposure to alcohol during adolescence decreased the amplitude of GABAA receptor (GABAA R)-mediated tonic currents
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